Results 61 to 70 of about 14,850 (297)

In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers [PDF]

, 2017
Citation: Wakizaka, M., Eshima, H., Tanaka, Y., Shirakawa, H., Poole, D. C., & Kano, Y. (2017). In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers. Physiological Reports, 5(5), 10.
Eshima, H., Kano, Y., Poole, David C., Shirakawa, H., Tanaka, Y., Wakizaka, M.   +5 more
core   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats

International Journal of Endocrinology, 2018
Diabetics have a higher risk of developing cerebral vasospasms (CVSP) than nondiabetics. The addition of the ryanodine receptor (RyR) blocker dantrolene to standard therapies reduces vasospasms in nondiabetics.
Maria J. Crespo, Marie Roman, Jonathan Matias, Myrna Morales, Hector Torres, Jose Quidgley   +5 more
doaj   +1 more source

Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases

Clinical Case Reports, 2022
Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality.
Xiaowei Chi, Yi Xu, Hongbing Liao, Tao Chen, Qiang Li, Qiang Fu   +5 more
doaj   +1 more source

Investigation of the Possible Protective Effects of Ketamine and Dantrolene on the Hippocampal Apoptosis and Spatial Learning in Rats Exposed to Repeated Electroconvulsive Seizures as a Model of Status Epilepticus.

Turkish Neurosurgery, 2020
AIM Status epilepticus (SE) may lead to cognitive dysfunction and neuronal loss in hippocampus. The aim of this study was to evaluate the possible neuroprotective effects of ketamine and dantrolene on the hippocampal apoptosis and spatial learning in ...
I. D. Gursoy, S. Barun, R. Erdem, U. Keskin, M. Kiziltas, P. Atilla, S. Muftuoglu, D. Yuce, F. Narin, M. Ertunç, Y. Sara, H. Canpınar   +11 more
semanticscholar   +1 more source

Combination Therapy of Allopurinol and Dantrolene and Its Role In The Prevention of Experimental Ischemia Reperfusion Injury Of The Small Intestine

Journal of Investigative Surgery, 2021
Background The effect of different drugs on ischemia and reperfusion (I/R; induced oxygen free radical damage) was examined in small bowel tissue because the intestine is extremely sensitive to this pathology. Different drugs (allopurinol and dantrolene)
Beatriz Prieto-Moure, Dolores Cejalvo-Lapeña, Mariola Belda-Antolí, Carolina Padrón-Sanz, José Miguel Lloris-Cejalvo, José Miguel Lloris-Carsí   +5 more
doaj   +1 more source

Effects of extracellular Ca++, K+, and Na+ on cone and retinal pigment epithelium retinomotor movements in isolated teleost retinas. [PDF]

, 1984
We have examined the effects of changes in extracellular ionic composition on cone and retinal pigment epithelium (RPE) retinomotor movements in cultured isolated teleost retinas.
BURNSIDE, Beth, Dearry, A
core   +4 more sources

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

A Case of Fatal Malignant Hyperthermia During Pes Equinovarus Surgery in a Child

Journal of Pediatric Emergency and Intensive Care Medicine, 2018
Malignant hyperthermia (MH) is a genetic syndrome characterized by hyperthermia, tachycardia, acidosis, and muscle rigidity, often triggered by depolarizing muscle relaxants such as volatile anesthetics and/or succinylcholine.
Ümüt Altuğ, Fulya Kamit Can, Ayşe Berna Anıl, Fatih Durak, Meltem Çakmak, Gökçen Özçifçi   +5 more
doaj   +1 more source

Memory and Learning Deficits Are Associated With Ca2+ Dyshomeostasis in Normal Aging

Frontiers in Aging Neuroscience, 2020
Neuronal intracellular Ca2+ homeostasis is critical to the normal physiological functions of neurons and neuronal Ca2+ dyshomeostasis has been associated with the age-related decline of cognitive functions.
Arkady Uryash, Valentina Flores, Jose A. Adams, Paul D. Allen, Jose R. Lopez   +4 more
doaj   +1 more source