Results 51 to 60 of about 4,800 (169)
Journal of Multidisciplinary Healthcare, 2022 Lingcan Tan,1,* Yi Teng,1,* Hong Yu,1 Chunyuan Liu,2 Kun Xiao,3 Jin Yin,4 Yunxia Zuo,1 Tao Zhu,1 Xiaoqian Deng1 1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2Department of ...
Tan L +8 more
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Malignant Hyperthermia in Sweden: Clinical Presentations and Genetic Findings
Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.ABSTRACT Introduction Malignant hyperthermia (MH) is a pharmacogenetic, hypermetabolic and potentially lethal reaction to potent volatile anaesthetics and the muscle relaxant succinylcholine. To improve the understanding of MH, the aim of this retrospective study was to describe the Swedish cohort with respect to clinical manifestations, demographics ...
Anna Hellblom +2 more
wiley +1 more source
A Case of Fatal Malignant Hyperthermia During Pes Equinovarus Surgery in a Child
Journal of Pediatric Emergency and Intensive Care Medicine, 2018 Malignant hyperthermia (MH) is a genetic syndrome characterized by hyperthermia, tachycardia, acidosis, and muscle rigidity, often triggered by depolarizing muscle relaxants such as volatile anesthetics and/or succinylcholine.
Ümüt Altuğ +5 more
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Management of spasticity in children with cerebral palsy
Acta Orthopaedica et Traumatologica Turcica, 2020 Management of spasticity is a major challenge to the rehabilitation team. The initial management has centered on the elimination of externally exacerbating causes, physical therapy, splinting and casting.
Dennis J. Matthews, Birol Balaban
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Advanced Science, Volume 13, Issue 36, 29 June 2026.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Acta Medica Iranica, 2016 Ryanodine receptor abnormalities has implicated in the generation and maintenance of seizure. Dantrolene, a selective ryanodine receptor antagonist, may be a potential drug for the prevention of seizure.
Mojtaba Keshavarz +2 more
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ChemSusChem, Volume 19, Issue 9, 14 May 2026.A Safe and Sustainable by Design (SSbD) mechanochemical approach was used to prepare a marketed sweetener from a biomass derivative used in flavoring industry. A personal care ingredient was also synthesized. The study also evaluated and compared the reactivity in of polymeric jars with that in of common conventional stainless steel or and zirconium ...
Rubén Solórzano‐Rodríguez +6 more
wiley +1 more source
EFFECTS OF DANTROLENE ON ACETYLCHOLINE-INDUCED CONTRACTIONS OF ISOLATED MOUSE ILEUM
Eurasian Journal of Medicine, 2019 Effect of skeletal muscular relaxant, dantrolene, on isolated longitudinal smooth muscle of mouse ileum of which contractions were induced by 10-6 M of acetylcholine (ACh) was investigated. Studies were performed in Tyrode solution. The first ACh-induced
Fatma Göçer +4 more
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2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C
Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot +33 more
wiley +1 more source