Results 61 to 70 of about 10,940 (260)
Malignant hyperthermia (literature review)
Вестник анестезиологии и реаниматологии, 2023 The objective – to summarize the current literature data on the etiology, pathogenesis, diagnosis and treatment of malignant hyperthermia. The search and analysis of literature data on malignant hyperthermia in the medical information systems PubMed ...
R. R. Tukhvatullina, N. V. Matinyan
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Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle [PDF]
, 2003 SummaryDNA methylation is a covalent biochemical modification controlling chromatin structure and gene expression. Exercise elicits gene expression changes that trigger structural and metabolic adaptations in skeletal muscle.
Barrès, Romain +9 more
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ChemSusChem, Volume 19, Issue 9, 14 May 2026.A Safe and Sustainable by Design (SSbD) mechanochemical approach was used to prepare a marketed sweetener from a biomass derivative used in flavoring industry. A personal care ingredient was also synthesized. The study also evaluated and compared the reactivity in of polymeric jars with that in of common conventional stainless steel or and zirconium ...
Rubén Solórzano‐Rodríguez +6 more
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Open Medicine, 2023 Malignant hyperthermia (MH) is an inherited skeletal muscle disorder caused primarily by a genetic mutation, usually in the calcium channel gene of the muscle. This mutation can lead to muscle hypersensitivity to volatile anesthetics (such as sevoflurane)
Lan Haiyan +6 more
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Frontiers in Cardiovascular Medicine, 2023 Calcific aortic valve disease (CAVD), a fibrocalcific thickening of the aortic valve leaflets causing obstruction of the left ventricular outflow tract, affects nearly 10 million people worldwide. For those who reach end-stage CAVD, the only treatment is
Christopher B. Sylvester +9 more
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Nuclear calcium signaling evoked by cholinergic stimulation in hippocampal CA1 pyramidal neurons [PDF]
, 2002 The cholinergic system is thought to play an important role in hippocampal-dependent learning and memory. However, the mechanism of action of the cholinergic system in these actions in not well understood.
Power, JM, Sah, P
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2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C
Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot +33 more
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Acta Medica Iranica, 2016 Ryanodine receptor abnormalities has implicated in the generation and maintenance of seizure. Dantrolene, a selective ryanodine receptor antagonist, may be a potential drug for the prevention of seizure.
Mojtaba Keshavarz +2 more
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Dantrolene is neuroprotective in Huntington's disease transgenic mouse model
Molecular Neurodegeneration, 2011 Background Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine expansion in the Huntingtin protein which results in the selective degeneration of striatal medium spiny neurons (MSNs).
Chen Xi +5 more
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Influence of ER leak on resting cytoplasmic Ca2+ and receptormediated Ca2+ signalling in human macrophage [PDF]
, 2017 Mechanisms controlling endoplasmic reticulum (ER) Ca2+ homeostasis are important regulators of resting cytoplasmic Ca2+ concentration ([Ca2+]cyto) and receptor-mediated Ca2+ signalling.
Fountain, Samuel J., Layhadi, Janice A.
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