Results 101 to 110 of about 400 (184)

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants. [PDF]

open access: yesRetrovirology, 2012
Johnson BC   +11 more
europepmc   +1 more source

Developmental aspects of xenobiotic transformation. [PDF]

open access: yesEnviron Health Perspect, 1976
Klinger W, Muller D.
europepmc   +1 more source

Improving the anti-HIV-1 activity and solubility of poorly water-soluble DAPYs by heteroaromatic replacement strategy: From naphthalene-DAPYs to quinoline-DAPYs

open access: closedBioorganic Chemistry, 2023
To enhance the anti-HIV-1 efficacy and solubility of our previously documented NNRTI 1, a collection of innovative quinoline-substituted DAPY derivatives were devised using heteroaromatic replacement strategy. The results of biological evaluation revealed that the representative compound 5h possessed the highest inhibitory activity against wild-type ...
Ruo-Lan Zhou   +5 more
semanticscholar   +4 more sources

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