Results 101 to 110 of about 198 (126)

Evolution of anti-HIV drug candidates. Part 3: diarylpyrimidine (DAPY) analogues

, 2001
The synthesis and anti-HIV-1 activity of a series of diarylpyrimidines (DAPYs) are described. Several members of this novel class of non-nucleoside reverse transcriptase inhibitors (NNRTIs) are extremely potent against both wild-type and a panel of ...
Donald Ludovici, Bart L. De Corte, Michael J. Kukla, Hong Ye, Chih Y. Ho, Mark. A. Lichtenstein, Robert W. Kavash, Koen Andries, Marie-Pierre de Béthune, Hilde Azijn, Rudi Pauwels, Paul Lewi, Jan Heeres, Lucien M. H. Koymans, Marc R. de Jonge, Koen Van Aken, Frederik F. D. Daeyaert, Kalyan Das, Eddy Arnold, Paul A. J. Janssen   +19 more
openalex   +2 more sources

QSAR modeling of anti-HIV activity for DAPY-like derivatives using the mixture of ligand-receptor binding information and functional group features as a new class of descriptors

, 2020
Mozhgan Beglari, Nasser Goudarzi, Davood Shahsavani, Mansour Arab Chamjangali, Rahele Dousti   +4 more
openalex   +1 more source

The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)

, 2007

openalex   +1 more source

SAR and QSAR studies: Modelling of new DAPY derivatives

, 2007
Abhilash Thakur, Mamta Thakur, Arpan Bharadwaj, Suprajnya Thakur   +3 more
openalex   +1 more source

Combination of 2D and 3D-QSAR studies on DAPY and DANA derivatives as potent HIV-1 NNRTIs

, 2021
Xiao Ding, Dongwei Kang, Lin Sun, Peng Zhan, Xinyong Liu   +4 more
openalex   +1 more source

Synthesis and structure–activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs

, 2011
Shuang‐Xi Gu, Qiuqin He, Shiqiong Yang, Xiaodong Ma, Fen‐Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque   +7 more
openalex   +1 more source

DAPY, dapy

, 2020
X.P. Brannmjk
openalex   +1 more source

HIV-1 Reverse Transcriptase in complex with a 2,6-difluorophenyl DAPY analog

, 2016
E.B. Lansdon
openalex   +1 more source

Improving the anti-HIV-1 activity and solubility of poorly water-soluble DAPYs by heteroaromatic replacement strategy: From naphthalene-DAPYs to quinoline-DAPYs

, 2023
Ruo-Lan Zhou, Chao Yu, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen‐Er Chen   +5 more
openalex   +1 more source

ChemInform Abstract: Evolution of Anti‐HIV Drug Candidates. Part 3. Diarylpyrimidine (DAPY) Analogues.

, 2002
Bart L. De Corte, Michael J. Kukla, et al. et al.   +2 more
openalex   +1 more source