Results 41 to 50 of about 112 (105)

An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. [PDF]

J Med Chem
Fabbrizi E, Chernyshov VV, Fiorentino F, Sbardella G, Ragno R, Nawrozkij M, Ivanov R, Rotili D, Mai A.   +8 more
europepmc   +1 more source

In silico studies of diarylpyridine derivatives as novel HIV-1 NNRTIs using docking-based 3D-QSAR, molecular dynamics, and pharmacophore modeling approaches. [PDF]

RSC Adv, 2018
Wan Y, Tian Y, Wang W, Gu S, Ju X, Liu G.   +5 more
europepmc   +1 more source

Focus on Chirality of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. [PDF]

Molecules, 2016
Famiglini V, Silvestri R.
europepmc   +1 more source

Development of diarylpyrimidine derivatives (& other heterocycles) as HIV-1 and WT RT inhibitors. [PDF]

RSC Med Chem
Dorababu A.
europepmc   +1 more source

Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variants. [PDF]

Acta Pharm Sin B
Wang Z, Zhang H, Gao Z, Sang Z, De Clercq E, Pannecouque C, Kang D, Zhan P, Liu X.   +8 more
europepmc   +1 more source

Molecular Docking Studies of HIV-1 Resistance to Reverse Transcriptase Inhibitors: Mini-Review. [PDF]

Molecules, 2018
Tarasova O, Poroikov V, Veselovsky A.
europepmc   +1 more source

Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery. [PDF]

ACS Med Chem Lett, 2018
Kang D, Wang Z, Zhang H, Wu G, Zhao T, Zhou Z, Huo Z, Huang B, Feng D, Ding X, Zhang J, Zuo X, Jing L, Luo W, Guma S, Daelemans D, Clercq E, Pannecouque C, Zhan P, Liu X.   +19 more
europepmc   +1 more source

Pyrimidine 2,4-Diones in the Design of New HIV RT Inhibitors. [PDF]

Molecules, 2019
Romeo R, Iannazzo D, Veltri L, Gabriele B, Macchi B, Frezza C, Marino-Merlo F, Giofrè SV.   +7 more
europepmc   +1 more source

NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities. [PDF]

Sci Rep, 2015
Thammaporn R, Yagi-Utsumi M, Yamaguchi T, Boonsri P, Saparpakorn P, Choowongkomon K, Techasakul S, Kato K, Hannongbua S.   +8 more
europepmc   +1 more source

Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles. [PDF]

Sci Adv
Wang Z, Rumrill S, Kang D, Guma SD, Feng D, De Clercq E, Pannecouque C, Chen CH, Arnold E, Ruiz FX, Liu X, Zhan P.   +11 more
europepmc   +1 more source