Results 81 to 90 of about 112 (105)

Lack of specificity of DA/DAPI fluorescence

Clinical Genetics, 1990
Cytogenetic studies showed 47,XY, + mar in a developmentally retarded child with some features of Prader‐Willi syndrome, and 46,XX in his mother. The marker chromosome showed a single subterminal primary constriction, bisatellites, and two C‐bands. DA/DAPI staining showed two intense bands in the marker chromosome, which most likely was derived from ...
M S, Lin, K H, Huynh, A, Fujimoto, M G, Wilson   +3 more
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Characterization of a DAPI-RIT-DAPI System for Gas-Phase Ion/Molecule and Ion/Ion Reactions

Journal of the American Society for Mass Spectrometry, 2013
The discontinuous atmospheric pressure interface (DAPI) has been developed as a facile means for efficiently introducing ions generated at atmospheric pressure to an ion trap in vacuum [e.g., a rectilinear ion trap (RIT)] for mass analysis. Introduction of multiple beams of ions or neutral species through two DAPIs into a single RIT has been previously
Ziqing, Lin, Lei, Tan, Sandilya, Garimella, Linfan, Li, Tsung-Chi, Chen, Wei, Xu, Yu, Xia, Zheng, Ouyang   +7 more
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DAPI: a DNA-Specific Fluorescent Probe

Biotechnic & Histochemistry, 1995
DAPI (4',6-diamidino-2-phenylindole) is a DNA-specific probe which forms a fluorescent complex by attaching in the minor grove of A-T rich sequences of DNA. It also forms nonfluorescent intercalative complexes with double-stranded nucleic acids.
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DAPI as a Useful Stain for Nuclear Quantitation

Biotechnic & Histochemistry, 1991
A simple-to-use fluorescent stain, 4',6-diamidino-2-phenylindole (DAPI), visualizes nuclear DNA in both living and fixed cells. DAPI staining was used to determine the number of nuclei and to assess gross cell morphology. Following light microscopic analyses, the stained cells were processed for electron microscopy.
B I, Tarnowski, F G, Spinale, J H, Nicholson   +2 more
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Effects of DAPI on human leukocytes in vitro

Cytogenetic and Genome Research, 1979
DAPI (4’-6-diamidino-2-phenylindole), a fluorochrome specific for AT-rich DNA, was supplied for 24 h at various concentrations to human leukocytes in culture. This treatment caused the appearance on the chromosomes of specific areas lacking spiralization. In particular, the centromeric regions of chromosomes 1, 9, and 16, a short region on the long arm
A, Rocchi, M, Di Castro, G, Prantera
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DNA directed damage using a brominated DAPI derivative

Chemical Communications, 2019
Conversion of a DNA-binding fluorophore (DAPI) to a photosensitizer via bromination retains high fluorescence and high affinity DNA binding but now produces light-induced reactive oxygen species directed towards DNA resulting in rapid cancer cell death.
Elyse M. Digby, Rahul Rana, Mark Nitz, Andrew A. Beharry   +3 more
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Blastobasis dapis Adamski, new species

2013
Blastobasis dapis Adamski, new species (Figs. 6, 69–70, 278, 321, Map 5) Diagnosis.— Blastobasis dapis is similar to B. balucis in facies but differs from the latter by having a wider gnathos; a narrower anal opening; a shorter apical process of the ventral part of the valva; a more protuberant ventral margin of the proximal flange of the dorsal part ...
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DAPI Staining and Fluorescence Microscopy Techniques for Phytoplasmas

2012
The 4',6-diamidino-2-phenylindole (DAPI) stain technique is a simple method that was developed for confirming the presence of phytoplasmas in hand-cut or freezing microtome sections of infected tissues. DAPI binds AT-rich DNA preferentially, so that phytoplasmas, localized among phloem cells, can be visualized in a fluorescence microscope.
Nancy M, Andrade, Nolberto L, Arismendi
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Reverse fluorescent chromosome banding with chromomycin and DAPI

Chromosoma, 1976
Two DNA binding guanine-specific antibiotics, chromomycin A3 (CMA) and the closely related mithramycin (MM), were used as chromosome fluorescent dyes. Root-tip metaphase chromosomes of three plant species and human metaphase chromosomes were sequentially stained with CMA or MM and the DNA binding AT-specific fluorochrome 4'-6-diamidino-2-phenylindole ...
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Structure-based discovery of novel piperidine-biphenyl-DAPY derivatives as non-nucleoside reverse transcriptase inhibitors featuring improved potency, safety, and selectivity: From piperazine-biphenyl-DAPYs to piperidine-biphenyl-DAPYs

European Journal of Medicinal Chemistry
Starting from our previously reported nonnucleoside reverse transcriptase inhibitor (NNRTI, 3), continuous efforts were made to enhance its potency and safety through a structure-based drug design strategy. This led to the discovery of a series of novel piperidine-biphenyl-diarylpyrimidines (DAPYs). Compound 10p, the most active compound in this series,
Wen-Juan, Huang, Christophe, Pannecouque, Erik, De Clercq, Shuai, Wang, Fen-Er, Chen   +4 more
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