Results 71 to 80 of about 917,675 (340)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
, 2014 If cold dark matter consists of particles, these must be non-interacting and non-relativistic by definition. In most cold dark matter models however, dark matter particles inherit a non-vanishing velocity dispersion from interactions in the early ...
Armendariz-Picon, Cristian +1 more
core +1 more source
A closer look at dark matter production in exponential growth scenarios
Journal of High Energy PhysicsWe investigate a recently proposed non-thermal mechanism for dark matter production, in which a small initial dark matter (χ) number density undergoes exponential growth through scatterings with bath particles (ϕ) in the early universe (χϕ → χχ).
Disha Bhatia
doaj +1 more source
The Astrophysical Journal, 2022 Stellar streams from globular clusters (GCs) offer constraints on the nature of dark matter and have been used to explore the dark matter halo structure and substructure of our Galaxy. Detection of GC streams in other galaxies would broaden this endeavor
Sarah Pearson +7 more
doaj +1 more source
On the Spatial Distribution of Dark Matter Halos
The Astrophysical Journal, 1998 We study the spatial distribution of dark matter halos in the Universe in terms of their number density contrast, related to the underlying dark matter fluctuation via a non-local and non-linear bias random field. The description of the matter dynamics is simplified by adopting the `truncated' Zel'dovich approximation to obtain both analytical results ...
CATELAN P. +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Capture of dark matter by the Solar System. Simple estimates
, 2010 We consider the capture of galactic dark matter by the Solar System, due to the gravitational three-body interaction of the Sun, a planet, and a dark matter particle.
I. B. KHRIPLOVICH +3 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Dark Matter at the End of the Galaxy
, 2010 Dark matter density profiles based upon Lambda-CDM cosmology motivate an ansatz velocity distribution function with fewer high velocity particles than the Maxwell-Boltzmann distribution or proposed variants.
A. S. Eddington +8 more
core +1 more source
Figure Rotation of IllustrisTNG Halos
The Astrophysical Journal, 2023 We use the TNG50 and TNG50 dark matter (DM)-only simulations from the IllustrisTNG simulation suite to conduct an updated survey of halo figure rotation in the presence of baryons.
Neil Ash, Monica Valluri
doaj +1 more source