Results 121 to 130 of about 12,937,092 (315)
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Geoforum PerspektivSpatial data science is an emerging field building on geographic information science, geography, and data science. Here we first discuss the definition and history of the field, arguing that it indeed warrants a new label. Then, we present the design of
Ane Rahbek Vierø, Michael Szell
doaj +1 more source
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
Handbook Of Soviet Social Science Data. Edited by Ellen Mickiewicz. Foreword by Karl W. Deutsch. New York: Free Press. London: Collier-Macmillan, 1973. xxvi, 225 pp. $14.95. [PDF]
, 1975 Robert Sharlet
openalex +1 more source
FEBS Letters, EarlyView.The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff +4 more
wiley +1 more source
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
Automating biomedical data science through tree-based pipeline optimization
, 2016 Over the past decade, data science and machine learning has grown from a mysterious art form to a staple tool across a variety of fields in academia, business, and government.
Andrews, Peter C. +5 more
core
Data Science Degree Apprentice
Patterns, 2020 In September 2019, 27 apprentices enrolled in the Level 6 Applied Data Science Degree Apprenticeship program, the first of its type in Wales. This article details the experiences of an apprentice on the course who works in the Data Science Campus at the ...
Evie Brown
doaj
Responsible Data Science [PDF]
Proceedings of the 2019 International Conference on Management of Data, 2019 Data science is an emerging discipline that offers both promise and peril. Responsible data science refers to efforts that address both the technical and societal issues in emerging data-driven technologies. How can machine learning and database systems reason effectively about complex dependencies and uncertainty? Furthermore, how do we understand the
openaire +3 more sources