Results 121 to 130 of about 28,511,988 (353)

The operation of the National Space Science Data Center [PDF]

, 1967
J. I. Vette
openalex   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Symposium on information science. 8. An approach to the automated handling of chemical-biological data in a pharmaceutical firm [PDF]

, 1965
C W Durachta, Colin Schenk, Richard Dick, F M Sturtevant   +3 more
openalex   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Teaching spatial data science

Geoforum Perspektiv
Spatial data science is an emerging field building on geographic information science, geography, and data science. Here we first discuss the definition and history of the field, arguing that it indeed warrants a new label. Then, we present the design of
Ane Rahbek Vierø, Michael Szell
doaj   +1 more source

Automatic Data Processing in the Manchester College of Science and Technology: Prof. G. Black [PDF]

, 1964

openalex   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Responsible Data Science [PDF]

Proceedings of the 2019 International Conference on Management of Data, 2019
Data science is an emerging discipline that offers both promise and peril. Responsible data science refers to efforts that address both the technical and societal issues in emerging data-driven technologies. How can machine learning and database systems reason effectively about complex dependencies and uncertainty? Furthermore, how do we understand the
openaire   +3 more sources

Handbook Of Soviet Social Science Data. Edited by Ellen Mickiewicz. Foreword by Karl W. Deutsch. New York: Free Press. London: Collier-Macmillan, 1973. xxvi, 225 pp. $14.95. [PDF]

, 1975
Robert Sharlet
openalex   +1 more source