Results 71 to 80 of about 514,201 (245)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Off-topic English Essay Detection Model Based on Hybrid Semantic Space for Automated English Essay Scoring System

open access: yesMATEC Web of Conferences, 2018
Aiming at the problem that the lack of accurate and efficient off-topic detection model for current Automated English Scoring System in China, an unsupervised off-topic essay detection model based on hybrid semantic space was proposed. Firstly, the essay
Huang Guimin   +3 more
doaj   +1 more source

Language Model-Driven Topic Clustering and Summarization for News Articles

open access: yesIEEE Access, 2019
Topic models have been widely utilized in Topic Detection and Tracking tasks, which aim to detect, track, and describe topics from a stream of broadcast news reports.
Peng Yang, Wenhan Li, Guangzhen Zhao
doaj   +1 more source

MetaLDA: a Topic Model that Efficiently Incorporates Meta information

open access: yes, 2017
Besides the text content, documents and their associated words usually come with rich sets of meta informa- tion, such as categories of documents and semantic/syntactic features of words, like those encoded in word embeddings.
Buntine, Wray   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Bibliometric Analysis to Scan and Scrape New Datasets: It’s all about that BASS

open access: yesInternational Journal of Population Data Science, 2017
Objectives The main objective of this poster is to present a pilot project in determining emerging population health themes and identifying key research-enabling datasets ahead of time.
Karen Tingay   +2 more
doaj   +1 more source

Taste or Addiction?: Using Play Logs to Infer Song Selection Motivation

open access: yes, 2017
Online music services are increasing in popularity. They enable us to analyze people's music listening behavior based on play logs. Although it is known that people listen to music based on topic (e.g., rock or jazz), we assume that when a user is ...
EM Airoldi   +4 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Hybrid topic modeling method based on dirichlet multinomial mixture and fuzzy match algorithm for short text clustering

open access: yesJournal of Big Data
Topic modeling methods proved to be effective for inferring latent topics from short texts. Dealing with short texts is challenging yet helpful for many real-world applications, due to the sparse terms in the text and the high dimensionality ...
Mutasem K. Alsmadi   +8 more
doaj   +1 more source

Software framework for hyperparameters optimization of models with additive regularization

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
The processing of unstructured data, such as natural language texts, is one of the urgent tasks in the development of intelligent products. In turn, topic modeling as a method of working with unmarked and partially marked text data is a natural choice ...
M. A. Khodorchenko   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy