Results 121 to 130 of about 3,123 (186)

Caenorhabditis elegans decapping proteins: localization and functional analysis of Dcp1, Dcp2, and DcpS during embryogenesis

open access: yes, 2005
Though posttranscriptional regulation is important for early embryogenesis, little is understood regarding control of mRNA decay during development. Previous work defined two major pathways by which normal transcripts are degraded in eukaryotes.
Richard E. Davis   +3 more
core   +1 more source

Cellular distributions of Dcp2, Dhh1, Edc3, and Xrn1 overlap under heat stress conditions.

open access: yes, 2015
Localization patterns of Xrn1-GFP in control (A) and heat-stressed cells (B) were superimposed with the distributions of Dcp2-RFP (strain CRY1396), Dhh1-RFP (CRY2244) and Edc3-mCherry (CRY2245).
Tomas Grousl (382128)   +4 more
core   +1 more source

Evolutionary condensate biology and its scope in uncovering the molecular determinants of FUS and Dcp2 phase separation

open access: yesDiscover Molecules
Biomolecular condensates formed by liquid–liquid phase separation (LLPS) have emerged as fundamental components of intracellular organization. While their biophysical mechanisms are increasingly well understood, much less is known about how the ability ...
Pouria Dasmeh
doaj   +1 more source

Conformational control of eukaryotic mRNA decapping by Dcp2 [PDF]

open access: yes, 2011
The lifetime of eukaryotic messenger RNA is highly regulated by elements on both the 5' and 3' ends of the message. Methylated guanine "cap" on the 5' end of a message is critical for nuclear export, protein translation, and stability of a message.
Floor, Stephen N.
core  

mRNA Decapping Enzyme DCP2 Expression Correlates with Progression and Prognosis of Hepatocellular Carcinoma

open access: yes
Abstract mRNA decapping enzyme 2 (DCP2) is a key regulator of mRNA degradation, influencing RNA metabolism and gene expression. While implicated in various diseases, its role in hepatocellular carcinoma (HCC) remains unclear. This study explores DCP2 as a potential biomarker for HCC through bioinformatics and experimental analyses.
Tianyi Huang   +5 more
openaire   +1 more source

Automated FLIM-FRET Segmentation Within RNP Condensates. [PDF]

open access: yesBio Protoc
Powell ND, Marcus JM, Fahim LE, Lee JE.
europepmc   +1 more source

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