Results 71 to 80 of about 60,554,138 (296)

Nicotiana glauca whole-genome investigation for cT-DNA study

BMC Research Notes, 2018
Objective Nicotiana glauca (tree tobacco) is a naturally transgenic plant, containing sequences acquired from Agrobacterium rhizogenes by horizontal gene transfer. Besides, N. glauca contains a wide profile of alkaloids of medical interest.
Galina Khafizova, Pavel Dobrynin, Dmitrii Polev, Tatiana Matveeva   +3 more
doaj   +1 more source

Systematic Comparison of the Performances of De Novo Genome Assemblers for Oxford Nanopore Technology Reads From Piroplasm

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundEmerging long reads sequencing technology has greatly changed the landscape of whole-genome sequencing, enabling scientists to contribute to decoding the genetic information of non-model species.
Jinming Wang, Kai Chen, Qiaoyun Ren, Ying Zhang, Junlong Liu, Guangying Wang, Aihong Liu, Youquan Li, Guangyuan Liu, Jianxun Luo, Wei Miao, Jie Xiong, Hong Yin, Hong Yin, Guiquan Guan   +14 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Tamias minimus de novo genome assembly fasta file

, 2022
10X chromium de novo genome assembly for Tamais minimus.
John R. Demboski (12620280), Nathanael Herrera (12525145), Jeffrey M. Good (10907258)   +2 more
core   +1 more source

Comparing De Novo Genome Assembly: The Long and Short of It

PLoS ONE, 2011
Recent advances in DNA sequencing technology and their focal role in Genome Wide Association Studies (GWAS) have rekindled a growing interest in the whole-genome sequence assembly (WGSA) problem, thereby, inundating the field with a plethora of new formalizations, algorithms, heuristics and implementations.
Giuseppe Narzisi, Bud Mishra
openaire   +4 more sources

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Genome sequence of the Chlamydophila abortus variant strain LLG [PDF]

, 2011
Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-type strain S26/3.
Clark, Ewan M., Smith, David George Emslie, Longbottom, D., David G. E. Smith, Spalding, L., Livingstone, M., Vretou, E., Clark, E.M., David Longbottom, Longbottom, David, Lainson, Alex F., Lainson, F.A., Victoria I. Siarkou, Wheelhouse, Nick M., Morag Livingstone, Spalding, Lucy, Wheelhouse, Nick, Lainson, F Alex, Michelle Sait, Wheelhouse, N., Lucy Spalding, Siarkou, Victoria I, Sait, M., Ewan M. Clark, F. Alex Lainson, Siarkou, V.I., Evangelia Vretou, Siarkou, Victoria I., Smith, David, Sait, Michelle, Clark, Ewan M, Nick Wheelhouse, Livingstone, Morag, Smith, David G E, Smith, D.G.E., Vretou, Evangelia   +35 more
core   +1 more source

Stepwise large genome assembly approach: a case of Siberian larch (Larix sibirica Ledeb)

BMC Bioinformatics, 2019
Background De novo assembling of large genomes, such as in conifers (~ 12–30 Gbp), which also consist of ~ 80% of repetitive DNA, is a very complex and computationally intense endeavor.
Dmitry A. Kuzmin, Sergey I. Feranchuk, Vadim V. Sharov, Alexander N. Cybin, Stepan V. Makolov, Yuliya A. Putintseva, Natalya V. Oreshkova, Konstantin V. Krutovsky   +7 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

De novo assembly of a haplotype-resolved human genome

Nature Biotechnology, 2015
The human genome is diploid, and knowledge of the variants on each chromosome is important for the interpretation of genomic information. Here we report the assembly of a haplotype-resolved diploid genome without using a reference genome. Our pipeline relies on fosmid pooling together with whole-genome shotgun strategies, based solely on next ...
Hongzhi Cao, Honglong Wu, Ruibang Luo, Shujia Huang, Yuhui Sun, Xin Tong, Yinlong Xie, Binghang Liu, Hailong Yang, Hancheng Zheng, Jian Li, Bo Li, Yu Wang, Fang Yang, Peng Sun, Siyang Liu, Peng Gao, Haodong Huang, Jing Sun, Dan Chen, Guangzhu He, Weihua Huang, Zheng Huang, Yue Li, Laurent C A M Tellier, Xiao Liu, Qiang Feng, Xun Xu, Xiuqing Zhang, Lars Bolund, Anders Krogh, Karsten Kristiansen, Radoje Drmanac, Snezana Drmanac, Rasmus Nielsen, Songgang Li, Jian Wang, Huanming Yang, Yingrui Li, Gane Ka-Shu Wong, Jun Wang   +40 more
openaire   +7 more sources