Results 161 to 170 of about 97,756 (253)

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Konjac Glucomannan as a Gel-Forming Biopolymer for Transdermal Drug Delivery: Properties, Formulation Strategies, and Translational Challenges. [PDF]

Drug Des Devel Ther
Asis DAD, Wardhana YW, Chaerunisaa AY.
europepmc   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Advanced freeze-thaw production of fungal chitosan and its Ag-Cu nanocomposite: enhanced antimicrobial activity and <i>in vitro</i> cytotoxicity evaluation. [PDF]

RSC Adv
Abugu HO, Tatlıcı E, Kılıç A, Apohan E, Çağlar Yılmaz H, Yeşilada Ö, Erdemoğlu S.   +6 more
europepmc   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

New Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

Bioactive Chitosan Oligosaccharides Derived from Crab Shell Waste Stimulate Osteogenic Differentiation in Pre-Osteoblast Cells. [PDF]

Mar Drugs
Duangprom S, Janpan P, Songkoomkrong S, Namwongsa S, Amonruttanapun P, Saetan J, Sung Y, Prasattongosoth V, Saengkun Y, Tamtin M, Sobhon P, Kornthong N.   +11 more
europepmc   +1 more source

Structural and Rheological Properties of Chitosan‐Biochar Composites Prepared With Waste Biomass‐Derived Biochar

Polymer Engineering &Science, EarlyView.
Chitosan dispersions containing biochar derived from vine pruning residue showed increasing shear stress and improved thermal stability with loading. Flow behavior was described by the Bingham plastic model in all cases. These results support the valorization of agricultural waste in functional biopolymer formulations.
Ahmet Eser, Mehmet Sadrettin Zeybek, Mertcan Öksüz, Kamil Şirin   +3 more
wiley   +1 more source

Advances in sirtuin research in lung diseases (Review). [PDF]

Int J Mol Med
Xi S, Chen W, Li X, Wang Y, Ke Y.
europepmc   +1 more source

Degradation of Crystalline Si‐Based Solar Modules With Varying Material Combinations—Part I: Encapsulant Degradation

Progress in Photovoltaics: Research and Applications, EarlyView.
This work deals with the degradation of solar modules with varying material combinations under accelerated aging conditions. By in situ moisture measurements and simulations of oxygen ingress, the consumption of stabilizing additives and polymer degradation can be correlated spatially resolved with the penetrating stressors.
Robert Heidrich, Oscar Lacroix‐Andrivet, Nikola Babić, Lasse Baldauf, Julia Rendon, Marko Jankovec, Marko Topič, Camille Bainier, Anton Mordvinkin, Hervé Vezin, Simon Pondaven, Ralph Gottschalg   +11 more
wiley   +1 more source

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex. [PDF]

Nucleic Acids Res
Nam E, Valeriano MO, Wang ZA, Whedon SD, Jiang H, Zhang MX, DuBois-Coyne S, Haque IA, Jiang J, Ferreira J, Farnung L, Lee K, Cole PA.   +12 more
europepmc   +1 more source