Results 171 to 180 of about 83,086 (267)

Icariin attenuates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome through SIRT3-mediated TFAM deacetylation. [PDF]

Front Pharmacol
Sun M, Huang H, Wei C, Xing Y, Wu B.
europepmc   +1 more source

Mapping the Bioenergetic Landscape of Oral Cancer Stem Cells: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objectives Oral squamous cell carcinoma (OSSC) remains highly lethal, with resistance largely driven by cancer stem cells (CSCs). Mitochondrial reprogramming supports CSC redox control, self‐renewal, and survival. This systematic review aimed to synthesize mitochondrial mechanisms sustaining CSCs in OSCC and evaluate their therapeutic ...
Rodrigo Elísio de Sá, Rebeca Barbosa da Rocha, Benedito dos Santos Alves, Maria Eduarda de Araujo de Carvalho, Jayane da Silva Sousa, José Delano Barreto Marinho‐Filho, Ana Jérsia Araújo   +6 more
wiley   +1 more source

SIRT3 Regulates HMGCS2 Deacetylation and Influences Cholangiocarcinoma Progression via the Metabolism of Ketone Bodies. [PDF]

Hum Mutat
Liu S, You X, Wang D, Wang X, Yang Y, Chen F, Zheng J, Qi F, Sun W, Peng W, Xi J, Lu Z, Zhang D.   +12 more
europepmc   +1 more source

MYB Factors: Hubs of Plant Stress and Hormone Crosstalk

Plant Biotechnology Journal, EarlyView.
ABSTRACT MYB transcription factors function as main regulatory hubs that integrate environmental signals with multi‐hormonal pathways to synchronize plant growth, metabolism and stress responses. This review delineates the regulatory roles of MYB in the signalling pathway of salicylic acid, jasmonic acid, ethylene and abscisic acid signalling.
Aye Aye Htun, Ya Wang, Jiahao Liu, Zhiqiang Guo, Yi Zheng, Wenjie Wang, Shuting Ma, Aolin Jia, Yan Ren, Feng Chen   +9 more
wiley   +1 more source

FGF21-Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO3. [PDF]

Aging Cell
Wu ZL, Ran R, Xie QQ, Zhang C, Chen YJ, Cheng P, Wang KP, Zhang HH.   +7 more
europepmc   +1 more source

miR172‐AP2 Controls Age‐Dependent Regeneration Competence in Populus

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plants maintain remarkable regenerative potential, yet this capacity declines with developmental age, limiting clonal propagation and biotechnological applications. Here, we show that the miR172‐AP2 module serves as a central determinant of regeneration competence in Populus.
Kaiwen Lyu, Abdul Azeez, Victor Busov
wiley   +1 more source

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven <i>KLF6</i> expression in renal carcinoma. [PDF]

Oncol Rep
Zamberi NNM, Abuhamad AY, Yusuf SNHM, Rahman NQAA, Mohtar MA, Syafruddin SE.   +5 more
europepmc   +1 more source

Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette, Chloé Ilbert, Sébastien Aimé, Hoai‐Nam Truong, Marielle Adrian, Stéphane Bourque   +5 more
wiley   +1 more source

Integrating stress responses and secondary metabolism: the regulatory functions of histone deacetylases in medicinal plants. [PDF]

Front Plant Sci
Yang Y, Tang D, Zhang R, Liu M, Feng T.
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source