Results 191 to 200 of about 97,756 (253)

Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation. [PDF]

open access: yesExp Mol Med
Xiong Y   +9 more
europepmc   +1 more source

Alcohol consumption and cognitive function: A systematic review and dose–response meta‐analysis of 20 cohort studies

open access: yesAddiction, EarlyView.
Abstract Background and aims Amid ongoing debate on whether low‐to‐moderate alcohol consumption reduces cardiovascular risk, studies examining the association between alcohol consumption and cognitive function have reported inconsistent results. To quantitatively assess this association, we conducted a dose–response meta‐analysis of cohort studies ...
Sooyeun Choi, Youjin Je
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick   +7 more
wiley   +1 more source

Colloidal Deacetylation of Chitin Nanocrystals Results in Amorphous and Patchy Chitosan Chains. [PDF]

open access: yesACS Nano
Jin T   +8 more
europepmc   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Effect of chitosan‐containing desensitizers applied prior to bleaching on the physical properties of enamel

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the effects of adding chitosan (Chi) to desensitizing agents applied before dental bleaching on enamel properties. Bovine enamel specimens were allocated to seven groups (n = 12): no treatment (negative control), 2% NaF (positive control), 2% NaF + 2% Chi, 2% NaF + 5% Chi, 2% NaF + 5% KNO3, 2% NaF + 5% KNO3 + 2 ...
Júlia Barbato   +8 more
wiley   +1 more source

Protein acetylation in atherosclerosis: beyond inflammation to core cellular processes and therapeutic potential. [PDF]

open access: yesFront Immunol
Dong Z   +9 more
europepmc   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

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