Results 201 to 210 of about 83,086 (267)

Sirtuin 1 as an emerging exerkine in the aging process: unveiling its multifaceted biological roles. [PDF]

Biogerontology
de Araújo Leite PL, Maciel LA, Patricio RCB, Pereira GLC, de Oliveira Lamounier AS, da Silva Aguiar S, Sousa CV, de Sousa Neto IV, Simões HG.   +8 more
europepmc   +1 more source

Sustained Release and Therapeutic Evaluation of Simvastatin‐Loaded Bioglass–Chitosan Gel Formulation for Skin Regeneration and Wound Healing Potential

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
A multifunctional chitosan–gallic acid hydrogel incorporated with heparin modified Zn–Ag doped bioglass and simvastatin was synthesized for chronic wound healing. The system shows antioxidant, antimicrobial, and pro‐angiogenic properties, promoting cell proliferation and collagen production.
Durgesh Kumar, Suhela Tyeb, Baby Shruit Shukla, Vivek Verma, Nitesh Kumar   +4 more
wiley   +1 more source

HDAC8 impairs tight junctions in allergic rhinitis through Smad7 deacetylation. [PDF]

Front Immunol
Chang HH, Cao ZN, Dang PH, Wei M, Li Y, Zhang HP, Wang J.   +6 more
europepmc   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy, Emmanuel Anyachukwu Irondi, Abdulazeez Olamilekan Elemosho, Emmanuel Oladipo Ajani   +3 more
wiley   +1 more source

Evaluation of Formulation-Dependent Antimicrobial Activity and Plant Compatibility of Chitosan-Based Silver Nanoparticles. [PDF]

Mar Drugs
Hosney A, Matelionienė N, Drapanauskaitė D, Ullah S, Barčauskaitė K.   +4 more
europepmc   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1597-1609, September 2026.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito, Marieli Mariano Gonçalves Dias, Gabriel Ernesto Jara, Thayná Mendonça Avelino, Giovanna Blazutti Elias, Paulo Sergio Lopes de Oliveira, Ana Carolina Migliorini Figueira   +6 more
wiley   +1 more source

Honokiol Ameliorates Hepatic Lipid Accumulation by Deacetylating PPARG via SIRT3. [PDF]

Cells
Yang Y, Guo S, Luo W, Liu D, Kang X.
europepmc   +1 more source

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga, Silvia Frigo, Alessandro Cherubini, Eniada Rrapaj, Luca Valenti   +4 more
wiley   +1 more source

Role of HDAC6 in carcinomas. [PDF]

Discov Oncol
Chen P, Zhang YL.
europepmc   +1 more source

Sarcopenia and satellite cell homeostasis disruption: the dual function of NAD+ metabolism. [PDF]

Front Nutr
Li C, Ai Y, Yan J, Wu S.
europepmc   +1 more source