Results 221 to 230 of about 97,756 (253)

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

open access: yesObesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang   +4 more
wiley   +1 more source

Molecular origin of anisotropic shear elastoplasticity in chitin. [PDF]

open access: yesSci Adv
Wan Z   +9 more
europepmc   +1 more source

Mapping the Bioenergetic Landscape of Oral Cancer Stem Cells: A Systematic Review

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives Oral squamous cell carcinoma (OSSC) remains highly lethal, with resistance largely driven by cancer stem cells (CSCs). Mitochondrial reprogramming supports CSC redox control, self‐renewal, and survival. This systematic review aimed to synthesize mitochondrial mechanisms sustaining CSCs in OSCC and evaluate their therapeutic ...
Rodrigo Elísio de Sá   +6 more
wiley   +1 more source

miR172‐AP2 Controls Age‐Dependent Regeneration Competence in Populus

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plants maintain remarkable regenerative potential, yet this capacity declines with developmental age, limiting clonal propagation and biotechnological applications. Here, we show that the miR172‐AP2 module serves as a central determinant of regeneration competence in Populus.
Kaiwen Lyu, Abdul Azeez, Victor Busov
wiley   +1 more source

Histone deacetylation links jasmonic acid signaling to flower size control in rose. [PDF]

open access: yesMol Hortic
Chang Y   +11 more
europepmc   +1 more source

Plant NAOGAT (ArgJ) Structure Reveals Mechanism of Ornithine Biosynthesis, Preference for Acetylornithine and Susceptibility to Mangotoxin

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski   +3 more
wiley   +1 more source

CUDC-907 attenuates pulmonary fibrosis by reversing HDAC1-mediated SMAD4 deacetylation at lysine 45. [PDF]

open access: yesBiol Direct
Li Y   +12 more
europepmc   +1 more source

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