Results 211 to 220 of about 97,756 (253)

Advances in the Role of SIRT3 in Vascular Remodeling in Hypertension. [PDF]

Biomolecules
Wahid A, Islam MT, Rana MS, Parvin MM, Weng C, Tang X.   +5 more
europepmc   +1 more source

Plant cis‐regulatory grammar: Decoding the multidimensional code of transcriptional regulation for programmable crop engineering

Journal of Integrative Plant Biology, EarlyView.
This review decodes the grammar of plant cis‐regulatory elements, revealing that their function emerges from sequence, chromatin accessibility, 3D topology, and cell type context. It highlights how single‐cell omics, CRISPR dissection, and AI‐driven design converge to enable predictive engineering and crop improvement. ABSTRACT Cis‐regulatory elements (
Libin Zhang, Maoteng Li
wiley   +1 more source

HDAC3 as an Immunometabolic Rheostat: Molecular Mechanisms of Deacylation Plasticity, Lactylation Dynamics, and Spatiotemporal Regulation. [PDF]

Biomolecules
Bu Y, Li W, Li S, Hao Z, Gu B, Chen J.
europepmc   +1 more source

Finding the sweet spot: An exploration of environmental factors to optimize Ulva carbohydrate content and composition

Journal of Phycology, EarlyView.
Abstract Green macroalgae from the Ulva genus are rich in polysaccharides of interest, including ulvan, starch, and cellulose. However, their content and structure are impacted by environmental factors, which poses challenges for industrial applications, especially in the context of climate change.
Julie Grivotte, Zoë A. Popper
wiley   +1 more source

Design and Engineering of an Artificial Bifunctional N-Deacetylase/N-Sulfotransferase for the Biosynthesis of N-Sulfated Heparosan. [PDF]

Adv Sci (Weinh)
Xi X, Xu R, Wang D, Yin G, Wang X, Chen H, Du G, Chen J, Kang Z.   +8 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Correction: Targeting the oxidative microenvironment with a tannic acid-modified manganese dioxide nanozyme loaded with Honokiol nanoplatform to activate sirtuin 3-mediated deacetylation for alleviating cerebral ischemia-reperfusion injury. [PDF]

J Nanobiotechnology
Yang X, Cheng Y, Liu C, Chen Y, Wang Y, Li Z, Xiong Q, Zhang C.   +7 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

The histone deacetylase family in health and disease. [PDF]

Signal Transduct Target Ther
Wen R, Yang YH, Zhang T, Zhang SY, Yang XR, Zhang LY, Hao PH, Zheng Y, Yang N, Zhang TN.   +9 more
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source