Results 231 to 240 of about 20,358 (251)
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The roles of DEAD box helicases in the life cycle of HIV-1
The Lancet, 2015HIV/AIDS is the largest global public health problem; about 76 million people have been infected with HIV and 36 million people have already died. Existing antiviral treatment is successful but requires lifelong adherence and mostly targets viral factors. The virus mutates and evades both drugs and the human immune response.
Nyarie, Sithole +3 more
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A DEAD-box RNA helicase in the Escherichia coli RNA degradosome
Nature, 1996The Escherichia coli RNA degradosome is a multi-enzyme complex that contains the exoribonuclease polynucleotide phosphorylase (PNPase) and the endoribonuclease RNase E. Both enzymes are important in RNA processing and messenger RNA degradation. Here we report that enolase and RhlB are two other major components of the degradosome.
B, Py +3 more
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A Novel Human Homolog of a Dead-Box RNA Helicase Family
Biochemical and Biophysical Research Communications, 1994Putative cDNA clones for a nuclear antigen that cross-reacts with anti-human aldolase A monoclonal antibody MAb1A2 were isolated from the HeLa lambda gt11 cDNA library and a candidate clone (clone 3) was analyzed. The cDNA has an open reading frame (ORF) of 1,317 bp encoding a novel RNA helicase belonging to the DEAD RNA helicase family.
Y, Kitajima +4 more
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Deciphering the relevance of dead box RNA helicases in gliomagenesis and autophagy
Human CellDead-box RNA helicases (DDXs) are a family of proteins with roles in RNA metabolism, regulating processes such as RNA splicing, translation, and ribosome assembly. Recently, their functions have expanded to include essential roles in autophagy-a cellular degradation pathway crucial for maintaining homeostasis-and oncogenesis, notably in glioblastoma ...
Arpit, Sharma +4 more
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Structural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome
Proceedings of the National Academy of Sciences of the United States of America, 2021Jan Philip Wurm +2 more
exaly
Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay
Structure, 2017Chia-Liang Lin +2 more
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The cloning and characterization of a DEAD-Box RNA helicase from stress-responsive wheat
Physiological and Molecular Plant Pathology, 2014Li−Li Huang +2 more
exaly