Results 51 to 60 of about 13,299 (220)

Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients

Frontiers in Cell and Developmental Biology, 2021
Decidualization is driven by differentiation of human endometrial stromal cells (ESCs), and is a prerequisite for successful implantation and establishment of pregnancy.
Jiaxing Li, Jiaxing Li, Jia Qi, Jia Qi, Guangxin Yao, Guangxin Yao, Qinling Zhu, Qinling Zhu, Xinyu Li, Xinyu Li, Rui Xu, Rui Xu, Zhenyi Zhu, Zhenyi Zhu, Hanting Zhao, Hanting Zhao, Yuan Wang, Yuan Wang, Ying Ding, Ying Ding, Yun Sun, Yun Sun   +21 more
doaj   +1 more source

Deregulation of the endometrial stromal cell secretome precedes embryo implantation failure [PDF]

, 2017
STUDY QUESTION Is implantation failure following ART associated with a perturbed decidual response in endometrial stromal cells (EnSCs)? SUMMARY ANSWER Dynamic changes in the secretome of decidualizing EnSCs underpin the transition of a hostile ...
Aberkane, Asma, Baumgarten, Miriam N., Brosens, Jan J., Chan, Jerry K. Y., Lee, Yie Hou, Lucas, Emma S., Maruyama, Yojiro, Peter Durairaj, Ruban Rex, Polanski, Lukasz T., Quenby, Siobhan, Raine-Fenning, Nick, Van de Velde, Hilde   +11 more
core   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Differential gene expression in decidualized human endometrial stromal cells induced by different stimuli

Scientific Reports
Decidualization can be induced by culturing human endometrial stromal cells (ESCs) with several decidualization stimuli, such as cAMP, medroxyprogesterone acetate (MPA) or Estradiol (E2).
Yumiko Doi-Tanaka, Isao Tamura, Amon Shiroshita, Taishi Fujimura, Yuichiro Shirafuta, Ryo Maekawa, Toshiaki Taketani, Shun Sato, Norihiro Sugino   +8 more
doaj   +1 more source

Deletion of Arid1a in Reproductive Tract Mesenchymal Cells Reduces Fertility in Female Mice [PDF]

, 2016
Women with endometriosis can suffer from decreased fecundity or complete infertility via abnormal oocyte function or impaired placental-uterine interactions required for normal pregnancy establishment and maintenance.
Broaddus, Russell, Hawkins, Shannon M., Khatri, Shikha, Wang, Xiyin, Wang, Zhong   +4 more
core   +1 more source

Membranous dysmenorrhea and decidual casts: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Membranous dysmenorrhea, characterized by the expulsion of intact endometrial tissue rather than gradual dissolution during menstruation, occasionally presents as a decidual cast—a complete triangular mold of the uterine cavity. This poorly understood condition is likely underdiagnosed.
Lovisa Brehmer, Hedvig Engberg
wiley   +1 more source

Endometrial and decidual stromal precursors show a different decidualization capacity [PDF]

Reproduction, 2020
Abstract Endometrial stromal cells (EnSCs) and decidual stromal cells (DSCs) originate from fibroblastic precursors located around the vessels of the human nonpregnant endometrium and the pregnant endometrium (decidua), respectively.
Ruiz Magaña, Maria Jose, Puerta, Jose Maria, Martínez-Aguilar, Rocio, Llorca, Tatiana, Blanco, Osmany, Muñoz-Fernández, Raquel, Olivares, Enrique G, Ruiz-Ruiz, Carmen   +7 more
openaire   +4 more sources

The Mechanism of Insulin-Like Growth Factor II mRNA-Binging Protein 3 Induce Decidualization and Maternal-Fetal Interface Cross Talk by TGF-β1 in Recurrent Spontaneous Abortion

Frontiers in Cell and Developmental Biology, 2022
Recurrent spontaneous abortion (RSA) is defined as the loss of two or more consecutive intrauterine pregnancies that are clinically established early in pregnancy. To date, the etiology and underlying mechanisms of RSA remain unclear.
Rong-hui Zhu, Fang-fang Dai, Dong-yong Yang, Shi-yi Liu, Ya-jing Zheng, Ma-li Wu, Zhi-min Deng, Zi-tao Wang, Yu-wei Zhang, Wei Tan, Zhi-dian Li, Juan He, Xiao Yang, Xiao Yang, Min Hu, Yan-xiang Cheng   +15 more
doaj   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

The Promyelocytic Leukemia Zinc Finger Transcription Factor Is Critical for Human Endometrial Stromal Cell Decidualization. [PDF]

PLoS Genetics, 2016
Progesterone, via the progesterone receptor (PGR), is essential for endometrial stromal cell decidualization, a cellular transformation event in which stromal fibroblasts differentiate into decidual cells.
Ramakrishna Kommagani, Maria M Szwarc, Yasmin M Vasquez, Mary C Peavey, Erik C Mazur, William E Gibbons, Rainer B Lanz, Francesco J DeMayo, John P Lydon   +8 more
doaj   +1 more source