Results 41 to 50 of about 7,864 (179)

Sequencing Analysis Reveals Potential NAD+-Regulated Mechanisms in Endometrial Stromal Cell Decidualization Prior to Embryo Implantation

Clinical and Experimental Obstetrics & Gynecology
Background: This study aimed to investigate the role of nicotinamide adenine dinucleotide (NAD+) in endometrial decidualization prior to embryo implantation and to elucidate the underlying mechanism.
Ming-hui Liu, Yao Fu, Shuo Han
doaj   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Decidualization of Endometriosis in Macaques [PDF]

Veterinary Pathology, 2016
The decidua is the superficial portion of endometrium that transforms, or decidualizes, under the influence of progesterone to nourish the early embryo during pregnancy. Deciduae outside the uterus are found in nearly 100% of human pregnancies. This condition, known as deciduosis, may mimic malignancy, resulting in additional diagnostic procedures that
H M, Atkins, E D, Lombardini, D L, Caudell, S E, Appt, A, Dubois, J M, Cline   +5 more
openaire   +2 more sources

Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization

Reproductive Biology and Endocrinology
Background Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation.
Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm   +7 more
doaj   +1 more source

The Mechanism of Insulin-Like Growth Factor II mRNA-Binging Protein 3 Induce Decidualization and Maternal-Fetal Interface Cross Talk by TGF-β1 in Recurrent Spontaneous Abortion

Frontiers in Cell and Developmental Biology, 2022
Recurrent spontaneous abortion (RSA) is defined as the loss of two or more consecutive intrauterine pregnancies that are clinically established early in pregnancy. To date, the etiology and underlying mechanisms of RSA remain unclear.
Rong-hui Zhu, Fang-fang Dai, Dong-yong Yang, Shi-yi Liu, Ya-jing Zheng, Ma-li Wu, Zhi-min Deng, Zi-tao Wang, Yu-wei Zhang, Wei Tan, Zhi-dian Li, Juan He, Xiao Yang, Xiao Yang, Min Hu, Yan-xiang Cheng   +15 more
doaj   +1 more source

Agomelatine ameliorates abortion‐related alterations in rats: Insights from behavioural, biochemical and histological analyses

Experimental Physiology, EarlyView.
Abstract Abortion aetiology is critically linked to increased myometrial contractions and maternal psychological stress. Given the limited efficacy of current therapies such as progesterone, investigating novel therapeutic interventions is essential. Melatonin exerts reproductive benefits.
Mehtap Pervin, Zeynep Dila Oz, Ahmed Sait Bozyil, Orhan Sayin, Husna Batmaz, Serhat Hancer, Salih Burcin Kavak, Nevin Kocaman, Haluk Kelestimur, Emine Kacar   +9 more
wiley   +1 more source

Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage

Journal of Translational Medicine
Background Miscarriage is a frustrating complication of pregnancy that is common among women of reproductive age. Insufficient decidualization which not only impairs embryo implantation but disturbs fetomaternal immune-tolerance, has been widely regarded
Jie Zhang, Mingxing Xue, Jiefang Huang, Shan He, Lingqiao Zhu, Xiaonan Zhao, Bei Wang, Tingwang Jiang, Yanyun Zhang, Changhong Miao, Guoqiang Zhou   +10 more
doaj   +1 more source

Long-chain acyl-CoA synthetase-4 regulates endometrial decidualization through a fatty acid β-oxidation pathway rather than lipid droplet accumulation

Molecular Metabolism
Objective: Lipid metabolism plays an important role in early pregnancy, but its effects on decidualization are poorly understood. Fatty acids (FAs) must be esterified by fatty acyl-CoA synthetases to form biologically active acyl-CoA in order to enter ...
Hongshuo Zhang, Qianyi Sun, Haojie Dong, Zeen Jin, Mengyue Li, Shanyuan Jin, Xiaolan Zeng, Jianhui Fan, Ying Kong   +8 more
doaj   +1 more source

Extracellular signal-regulated kinase 1/2 signaling pathway is required for endometrial decidualization in mice and human. [PDF]

PLoS ONE, 2013
Decidualization is a crucial change required for successful embryo implantation and the maintenance of pregnancy. During this process, endometrial stromal cells differentiate into decidual cells in response to the ovarian steroid hormones of early ...
Chae Hyun Lee, Tae Hoon Kim, Jae Hee Lee, Seo Jin Oh, Jung-Yoon Yoo, Hyo Suk Kwon, Young Im Kim, Susan D Ferguson, Ji Yeon Ahn, Bon Jeong Ku, Asgerally T Fazleabas, Jeong Mook Lim, Jae-Wook Jeong   +12 more
doaj   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source