Results 41 to 50 of about 13,299 (220)

Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis

Journal of Biomedical Science, 2022
Background Sleep disturbance can cause adverse pregnancy outcomes by changing circadian gene expression. The potential mechanisms remain unclear.
Liyuan Cui, Feng Xu, Chunfang Xu, Yan Ding, Songcun Wang, Meirong Du   +5 more
doaj   +1 more source

Evaluation of human first trimester decidual and telomerase-transformed endometrial stromal cells as model systems of in vitro decidualization [PDF]

, 2011
Background Decidualization, the differentiation process of maternal uterine stromal cells into secretory decidual cells, is a prerequisite for successful implantation and progression of pregnancy.
Leila Saleh, Gerlinde R Otti, Christian Fiala, Jürgen Pollheimer, Martin Knöfler   +4 more
core   +2 more sources

Expression and function of kisspeptin during mouse decidualization. [PDF]

PLoS ONE, 2014
BACKGROUND: Plasma kisspeptin levels dramatically increased during the first trimester of human pregnancy, which is similar to pregnancy specific glycoprotein-human chorionic gonadotropin.
Peng Zhang, Min Tang, Ting Zhong, Yan Lin, Teng Zong, Chengxue Zhong, BaoPing Zhang, Min Ren, HaiBin Kuang   +8 more
doaj   +1 more source

Nuclear actin assembly is an integral part of decidualization in human endometrial stromal cells

Communications Biology
Decidualization of the human endometrium is critical for establishing pregnancy and is entailed by differentiation of endometrial stromal cells (ESCs) into decidual cells.
Isao Tamura, Kei Miyamoto, Chiharu Hatanaka, Amon Shiroshita, Taishi Fujimura, Yuichiro Shirafuta, Yumiko Mihara, Ryo Maekawa, Toshiaki Taketani, Shun Sato, Kazuya Matsumoto, Hiroshi Tamura, Norihiro Sugino   +12 more
doaj   +1 more source

Success after failure : the role of endometrial stem cells in recurrent miscarriage [PDF]

, 2016
Endometrial stem-like cells, including mesenchymal stem cells (MSCs) and epithelial progenitor cells, are essential for cyclic regeneration of the endometrium following menstrual shedding.
Brosens, Jan J., Dyer, Nigel P., Fishwick, Katherine, Lucas, Emma S., Ott, Sascha   +4 more
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

High incidence of decidualization failure in infertile women

Reproductive Medicine and Biology
Purpose Decidualization is an important event for embryo implantation and successful pregnancy. Impaired decidualization leads to implantation failure and miscarriage. However, it is unclear how often decidualization failure occurs in infertile women. By
Isao Tamura, Yumiko Doi‐Tanaka, Akihisa Takasaki, Katsunori Shimamura, Toshihide Yoneda, Hitomi Takasaki, Amon Shiroshita, Taishi Fujimura, Yuichiro Shirafuta, Norihiro Sugino   +9 more
doaj   +1 more source

Effects of Aurora kinase A on mouse decidualization via Stat3-plk1-cdk1 pathway

Reproductive Biology and Endocrinology, 2021
Background Decidualization is essential to the successful pregnancy in mice. The molecular mechanisms and effects of Aurora kinase A (Aurora A) remain poorly understood during pregnancy.
Peng-Chao Wang, Si-Ting Chen, Zeng-Ming Yang   +2 more
doaj   +1 more source

The glycosyltransferase EOGT regulates adropin expression in decidualizing human endometrium [PDF]

, 2017
In pregnancy, resistance of endometrial decidual cells to stress signals is critical for the integrity of the feto-maternal interface and, by extension, survival of the conceptus. O-GlcNAcylation is an essential post-translational modification that links
Alam, Mohammad T., Aplin, John D., Barros, Flavio S. V., Brosens, Jan J., Ewington, Lauren J., Muter, Joanne, Ruane, Peter T., Vrljicak, Pavle, Westwood, Melissa   +8 more
core   +2 more sources

Metroplasty before IVF in women with a T‐shaped uterus: A clinical challenge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract A T‐shaped uterus is a uterine malformation, which can be either congenital or acquired, potentially impairing fertility and increasing the risk of miscarriage. Diagnosis primarily relies on three‐dimensional ultrasound and hysteroscopy. Hysteroscopic metroplasty is the standard surgical intervention aimed at restoring normal uterine anatomy ...
Fabio Barra, Irene Gazzo, Alessandro Favilli, Consuelo Russo, Giulia Monaco, Franco Alessandri, Sandro Gerli, Luis Alonso Pacheco, Caterina Exacoustos, Simone Ferrero   +9 more
wiley   +1 more source