Results 31 to 40 of about 13,299 (220)

Progesterone-dependent induction of phospholipase C-related catalytically inactive protein 1 (PRIP-1) in decidualizing human endometrial stromal cells [PDF]

, 2016
Decidualization denotes the transformation of endometrial stromal cells into specialized decidual cells. In pregnancy, decidual cells form a protective matrix around the implanting embryo, enabling coordinated trophoblast invasion and formation of a ...
Blanks, Andrew M., Brighton, Paul, Brosens, Jan J., Lacey, Lauren, Lucas, Emma S., Muter, Joanne, Quenby, Siobhan, Shmygol, Anatoly   +7 more
core   +5 more sources

TGFβ superfamily signaling and uterine decidualization

Reproductive Biology and Endocrinology, 2017
Decidualization is an intricate biological process where extensive morphological, functional, and genetic changes take place in endometrial stromal cells to support the development of an implanting blastocyst.
Nan Ni, Qinglei Li
doaj   +1 more source

ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients

Cell Death and Disease, 2021
Decidualization is a complex process involving cellular proliferation and differentiation of the endometrial stroma and is required to establish and support pregnancy.
Zhilong Wang, Yang Liu, Jingyu Liu, Na Kong, Yue Jiang, Ruiwei Jiang, Xin Zhen, Jidong Zhou, Chaojun Li, Haixiang Sun, Guijun Yan   +10 more
doaj   +1 more source

SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualization

eLife, 2022
The establishment of pregnancy in human necessitates appropriate decidualization of stromal cells, which involves steroids regulated periodic transformation of endometrial stromal cells during the menstrual cycle.
Pinxiu Huang, Wenbo Deng, Haili Bao, Zhong Lin, Mengying Liu, Jinxiang Wu, Xiaobo Zhou, Manting Qiao, Yihua Yang, Han Cai, Faiza Rao, Jingsi Chen, Dunjin Chen, Jinhua Lu, Haibin Wang, Aiping Qin, Shuangbo Kong   +16 more
doaj   +1 more source

Uterine selection of human embryos at implantation [PDF]

, 2014
Human embryos frequently harbor large-scale complex chromosomal errors that impede normal development. Affected embryos may fail to implant although many first breach the endometrial epithelium and embed in the decidualizing stroma before being rejected ...
A Mertzanidou, B Cloke, B Crespi, BC Han, BM Forman, CH Weimar, D Emera, D Emera, D Haig, DM Benbrook, E Rajcan-Separovic, E Vanneste, EB Chuong, EM Heijnen, FU Hartl, G Teklenburg, GW Wong, H Yang, HH Kampinga, JJ Brosens, JJ Brosens, LA Kazal, M Furuhashi, M Iwaki, M Ohmuraya, M Salker, MD Stephenson, MS Salker, MS Salker, N Arimura, N Mansouri-Attia, N Sharma, N Sharma, NS Macklon, P Walter, R Rai, S Altmae, S Kaushik, S Quenby, T Iwawaki, T Kadowaki, Y Kabeya, YC Ruan, YH Yang, YJ Kim   +44 more
core   +2 more sources

Unique and independent role of the GABAB1 subunit in embryo implantation and uterine decidualization in mice

Genes and Diseases, 2021
Embryo implantation and decidualization are crucial for successful pregnancy, which include multiple genes and signaling pathways, while the precise mechanism regarding embryo implantation and decidualization has yet to be explored.
Wenhao Chen, Qian Zhang, Haibin Wang, Dongmei Tan, Yi Tan   +4 more
doaj   +1 more source

Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]

, 2018
Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng, Kommagani, Ramakrishna, Michalski, Stephanie   +2 more
core   +2 more sources

Regulation of the PI3K/Akt pathway during decidualization of endometrial stromal cells. [PDF]

PLoS ONE, 2017
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In order
François Fabi, Kathy Grenier, Sophie Parent, Pascal Adam, Laurence Tardif, Valérie Leblanc, Eric Asselin   +6 more
doaj   +1 more source

Uterine natural killer cell heterogeneity: Lessons from mouse models [PDF]

, 2020
Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes.
Sojka, Dorothy K
core   +1 more source

Analysis of chromatin accessibility in decidualizing human endometrial stromal cells [PDF]

, 2017
Spontaneous decidualization of the endometrium in response to progesterone signaling is confined to menstruating species, including humans and other higher primates.
Brosens, Jan J., Dyer, Nigel P., Lansdowne, Lauren, Lucas, Emma S., Lucciola, Raffaella, Muter, Joanne, Ott, Sascha, Vrljicak, Pavle   +7 more
core   +1 more source