Results 11 to 20 of about 7,864 (179)
RICTOR Prevents Decidualization Disorder in Women With Advanced Maternal Age via Regulating FoxO1 Nuclear Export. [PDF]
Aging CellAdvanced maternal age impairs uterine decidualization via downregulated RICTOR‐ATK3‐FoxO1 signaling. The RICTOR agonist MHY1485 rescues decidual defects, offering a therapy for age‐related pregnancy failure. ABSTRACT Miscarriage and abnormal embryonic development in women of advanced maternal age (AMA) are often associated with impaired decidualization.
Lin Y +9 more
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Structural Control of Stromal-Immune Coupling by COL24A1 Underlies Pregnancy Maintenance. [PDF]
Adv Sci (Weinh)COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Wu T +12 more
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Decidual cells and decidualization in the carnivoran endotheliochorial placenta
Frontiers in Cell and Developmental Biology, 2023 Decidualization is considered a distinctive feature of eutherian pregnancy, and has appeared during evolution along with the development of invasive forms of placentation, as the endotheliochorial placenta. Although decidualization is not massive in carnivores, as it is in most species developing hemochorial placentas, isolated or grouped cells ...
Mónica Elizabeth Diessler +5 more
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A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization
Frontiers in Endocrinology, 2022 Decidualization is the hormone-dependent process of endometrial remodeling that is essential for fertility and reproductive health. It is characterized by dynamic changes in the endometrial stromal compartment including differentiation of fibroblasts ...
Isaac W. Shaw +8 more
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Research progress on human endometrium decidualization In vitro cell models
Reproductive and Developmental Medicine, 2021 Decidualization is a special type of differentiation of endometrial stromal cells into secretory decidualized cells, which is closely related to the occurrence of menstruation and establishment of pregnancy. Decidualization abnormalities can cause female
Zhi-Jing Tang +3 more
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Systematic Analysis of the Molecular Mechanism Underlying Decidualization Using a Text Mining Approach. [PDF]
PLoS ONE, 2015 Decidualization is a crucial process for successful embryo implantation and pregnancy in humans. Defects in decidualization during early pregnancy are associated with several pregnancy complications, such as pre-eclampsia, intrauterine growth restriction
Ji-Long Liu, Tong-Song Wang
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Decidualization and Related Pregnancy Complications
Maternal-Fetal Medicine, 2022 . Decidualization is the differentiation of endometrial stromal cells into secretory decidual stromal cells. Human decidualization involves some amount of signaling molecules and pathways as well as genetic reprogramming, which is driven by the ...
Jing Tong +6 more
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Marker genes of decidualization: activation of the decidual prolactin gene [PDF]
Human Reproduction Update, 1998 Decidualization of human endometrial stromal (ES) cells in vitro is induced by cAMP analogues and ligands that elevate cellular cAMP levels in a manner resembling the gonadotrophins, prostaglandin E2 and relaxin (RLX). This differentiation process is marked by the onset of decidual prolactin (PRL) production in the late luteal phase of the cycle. Using
R, Telgmann, B, Gellersen
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Frontiers in Pharmacology, 2022 Impaired decidualization was recognized as one of the crucial pathomechanisms accounting for unexplained recurrent spontaneous abortion (URSA). Currently, the exact molecular mechanism and targeted clinical decision are still in exploration.
Xiaoxuan Zhao +5 more
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Taurodontism in deciduous molars [PDF]
BMJ Case Reports, 2013 Taurodont teeth are characterised by large pulp chambers at the expense of roots. An enlarged pulp chamber, apical displacement of the pulpal floor and no constriction at the level of the cement-enamel junction are the characteristic features of taurodont tooth.
Yash, Bafna +3 more
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