Results 131 to 140 of about 18,940 (249)

New insight of some extracellular matrix molecules in beef muscles. Relationships with sensory qualities

Animal, 2016
The aim of this study was to highlight the relationships between decorin, tenascin-X and type XIV collagen, three minor molecules of extracellular matrix (ECM), with some structural parameters of connective tissue and its content in total collagen, its ...
A. Dubost, D. Micol, C. Lethias, A. Listrat   +3 more
doaj   +1 more source

Patients With B3GALT6‐Linkeropathies Display Sialylated Disaccharides as Truncated Glycosaminoglycan Linkage Regions of Specific Core Proteins

Proteoglycan Research, Volume 4, Issue 3, July 2026.
ABSTRACT The Ehlers–Danlos syndromes (EDS) are a group of heritable connective tissue disorders, characterized by varying degrees of joint hypermobility, skin hyperextensibility and extracellular matrix defects. Spondylodysplastic type of EDS (spEDS) is a rare type of this group that can be caused by pathogenic variants in the B3GALT6 gene, coding for ...
Noborn Fredrik, Nilsson Jonas, Blomqvist Maria, Syx Delfien, Mendoza‐Londono Roberto, Malfait Fransiska, Larson Göran   +6 more
wiley   +1 more source

Decreased Serum Decorin Levels Are Correlated with Aortic Stiffness as Assessed Using Carotid–Femoral Pulse Wave Velocity in Patients with Peritoneal Dialysis

Life
In patients on chronic peritoneal dialysis (PD), aortic stiffness (AS) is a common cardiovascular condition that can predict cardiovascular events and mortality. Decorin is a small leucine-rich proteoglycan that plays a vital role in extracellular matrix
Yahn-Bor Chern, Po-Yu Huang, Yu-Li Lin, Chih-Hsien Wang, Jen-Pi Tsai, Bang-Gee Hsu   +5 more
doaj   +1 more source

Decorin, biglycan and their endocytosis receptor in rat renal cortex [PDF]

, 1998
Decorin, biglycan and their endocytosis receptor in rat renal cortex.BackgroundAmong the small proteoglycans, biglycan and decorin have been proposed to be potent modulators of TGF-β-mediated inflammatory kidney diseases.
Hausser, Heinz, Altenburger, Martin, Ugorcakova, Jana, Schaefer, Roland M., Fisher, Larry W., Kresse, Hans, August, Christian, Schaefer, Liliana   +7 more
core   +1 more source

PMN cell released proteases cleave decorin in vitro. [PDF]

, 2013
PMN cells were isolated from peripheral human blood and treated with vehicle or PMA. Conditioned media were collected and incubated with bovine decorin with or without protease inhibitors for 30 minutes. (A) Representative Western blot of decorin: Lane 1:
Wei Xia (349131), Yong Li (15029), Gary J. Fisher (179719), Ying Liu (18461), Henriette A. Remmer (452404), John Voorhees (452405)   +5 more
core   +1 more source

Cathepsin-S degraded decorin are elevated in fibrotic lung disorders – development and biological validation of a new serum biomarker

BMC Pulmonary Medicine, 2017
Background Decorin is one of the most abundant proteoglycans of the extracellular matrix and is mainly secreted and deposited in the interstitial matrix by fibroblasts where it plays an important role in collagen turnover and tissue homeostasis ...
S.N. Kehlet, C.L. Bager, N. Willumsen, B. Dasgupta, C. Brodmerkel, M. Curran, S. Brix, D.J. Leeming, M. A. Karsdal   +8 more
doaj   +1 more source

Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury

International Journal of Molecular Sciences, 2019
Bronchopulmonary dysplasia (BPD), caused by hyperoxia in newborns and infants, results in lung damage and abnormal pulmonary function. However, the current treatments for BPD are steroidal and pharmacological therapies, which cause neurodevelopmental ...
Jihye Kwon, Miyeon Kim, Y. Bae, Gee-Hye Kim, S. Choi, W. Oh, S. Um, H. Jin   +7 more
semanticscholar   +1 more source

Homeostatic Role of Decorin in Right Ventricular Pressure Overload and Pulmonary Hypertension Induced Remodeling

JACC: Basic to Translational Science
Summary: Right ventricular (RV) pressure loading induces RV profibrotic signaling and fibrosis associated with RV dysfunction. RV decorin protein levels are decreased in patients with chronic RV pressure loading.
Yohei Akazawa, MD, PhD, Sriram Vaidyanathan, PhD, Michael Bradley Dewar, MSc, Kana Yazaki, MD, PhD, John Dauz, MSc, Osami Honjo, MD, PhD, Mei Sun, MD, Golam Kabir, MD, Robert P. Jankov, MD, PhD, Scott Patrick Heximer, PhD, Kim A. Connelly, MD, PhD, Mark K. Friedberg, MD, PhD   +11 more
doaj   +1 more source

Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.

PLoS ONE, 2012
Background and aimDuring prostate development, mesenchymal-epithelial interactions regulate organ growth and differentiation. In adult prostate, stromal-epithelial interactions are important for tissue homeostasis and also play a significant role in ...
Alexander Henke, O Cathal Grace, George R Ashley, Grant D Stewart, Antony C P Riddick, Henry Yeun, Marie O'Donnell, Richard A Anderson, Axel A Thomson   +8 more
doaj   +1 more source

Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice

Scientific Reports, 2019
Studies have implicated the extracellular matrix (ECM) of adipose tissue in insulin resistance. The proteoglycan decorin, a component of ECM, has been associated with glucose tolerance, but possible causal effects on metabolism remain to be explored.
J. Svärd, T. Røst, Camilla E. N. Sommervoll, Christine Haugen, O. Gudbrandsen, A. E. Mellgren, E. Rødahl, J. Fernø, S. Dankel, J. Sagen, G. Mellgren   +10 more
semanticscholar   +1 more source