Results 111 to 120 of about 14,247 (218)

Allergen-induced asthma is decreased in decorin-deficient mice

, 2008
Decorin, is an extracellular matrix proteoglycan with important biological functions. Decorin deficiency affects collagen fibrillogenesis, airway mechanics, airway-parenchymal interdependence, and airway smooth muscle proliferation and apoptosis.
Marchica, Cinzia Loreta, 1984-
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Interaction of heparin cofactor II with biglycan and decorin

, 1993
Two small interstitial dermatan sulfate-containing proteoglycans, biglycan and decorin, are present in extracellular matrices of skin, tendon, ligament, and cartilage.

core   +1 more source

Lentiviral-Encoded shRNA Silencing of Proteoglycan Decorin Enhances Tendon Repair and Regeneration within a Rat Model

Cell Transplantation, 2013
Injured tendons often heal with scar tissue formation, resulting in uniformly smaller collagen fibrils and poor mechanical properties. The small leucine-rich proteoglycan decorin is well known to regulate fusion of collagen fibrils.
Ping Lu, Guo-Rong Zhang, You-Zhi Cai, Boon Chin Heng, Hao Ren, Lin-Lin Wang, Junfeng Ji, Xiao-Hui Zou, Hong-Wei Ouyang   +8 more
doaj   +1 more source

Decorin as a multivalent therapeutic agent against cancer.

, 2016
Decorin is a prototypical small leucine-rich proteoglycan that epitomizes the multifunctional nature of this critical gene family. Soluble decorin engages multiple receptor tyrosine kinases within the target-rich environment of the tumor stroma and tumor
Neill, Thomas, Iozzo, Renato V., Schaefer, Liliana   +2 more
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Domain structure elucidation of human decorin glycosaminoglycans

, 2010
The structure of the GAG (glycosaminoglycan) chain of recombinantly expressed decorin proteoglycan was examined using a combination of intact-chain analysis and domain compositional analysis.
Richard T. Owens, Robert J. Linhardt, Tatiana N. Laremore, Scott A. McCallum, Mellisa Ly, McCallum, Scott A., Kemal Solakyildirim, Linhardt, Robert J., Laremore, Tatiana N., Solakyildirim, Kemal, Owens, Richard T., Zhenqing Zhang, Ly, Mellisa, Zhang, Zhenqing   +13 more
core   +1 more source

Potential use of decorin in preventing cerebral vasospasm through the inhibition of transforming growth factor-beta activity: Insights from an experimental rabbit subarachnoid hemorrhage model

World Neurosurgery: X
Objective: The development of vasospasm after subarachnoid hemorrhage (SAH) is a major cause of death and disability. It leads to structural changes such as smooth muscle and myofibroblast proliferation, necrosis, intimal hyperplasia, and vascular ...
Betul Yaman, Gulce Gel, Cengiz Tuncer, Sahin Hanalioglu, Husamettin Bulut, Ata Turker Arikok, Bora Gurer, Erhan Turkoglu   +7 more
doaj   +1 more source

Role of Decorin Core Protein in Collagen Organisation in Congenital Stromal Corneal Dystrophy (CSCD).

PLoS ONE, 2016
The role of Decorin in organising the extracellular matrix was examined in normal human corneas and in corneas from patients with Congenital Stromal Corneal Dystrophy (CSCD).
Christina S Kamma-Lorger, Christian Pinali, Juan Carlos Martínez, Jon Harris, Robert D Young, Cecilie Bredrup, Eva Crosas, Marc Malfois, Eyvind Rødahl, Keith M Meek, Carlo Knupp   +10 more
doaj   +1 more source

Decorin, biglycan and their endocytosis receptor in rat renal cortex

, 1998
Decorin, biglycan and their endocytosis receptor in rat renal cortex.BackgroundAmong the small proteoglycans, biglycan and decorin have been proposed to be potent modulators of TGF-β-mediated inflammatory kidney diseases.
Hausser, Heinz, Altenburger, Martin, Ugorcakova, Jana, Schaefer, Roland M., Fisher, Larry W., Kresse, Hans, August, Christian, Schaefer, Liliana   +7 more
core   +1 more source

PMN cell released proteases cleave decorin in vitro.

, 2013
PMN cells were isolated from peripheral human blood and treated with vehicle or PMA. Conditioned media were collected and incubated with bovine decorin with or without protease inhibitors for 30 minutes. (A) Representative Western blot of decorin: Lane 1:
Wei Xia (349131), Yong Li (15029), Gary J. Fisher (179719), Ying Liu (18461), Henriette A. Remmer (452404), John Voorhees (452405)   +5 more
core   +1 more source

Decorin binding protein compositions

, 1998
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias.
Guo, Betty, Hook, Magnus
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