Results 91 to 100 of about 15,201 (170)
MT1-MMP-Mediated cleavage of decorin in corneal angiogenesis
, 2009 Background/Aims: Decorin has been shown to have antiangiogenic properties. In this study, we evaluate the involvement of membrane type 1-matrix metalloproteinase (MT1-MMP), a proangiogenic enzyme, in decorin cleavage in the cornea.
Chang, JH +7 more
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World Neurosurgery: XObjective: The development of vasospasm after subarachnoid hemorrhage (SAH) is a major cause of death and disability. It leads to structural changes such as smooth muscle and myofibroblast proliferation, necrosis, intimal hyperplasia, and vascular ...
Betul Yaman +7 more
doaj +1 more source
Allergen-induced asthma is decreased in decorin-deficient mice
, 2008 Decorin, is an extracellular matrix proteoglycan with important biological functions. Decorin deficiency affects collagen fibrillogenesis, airway mechanics, airway-parenchymal interdependence, and airway smooth muscle proliferation and apoptosis.
Marchica, Cinzia Loreta, 1984-
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Invasive human bladder cancer cells do not express decorin.
, 2013 Analyses were performed on the whole study population and representative images are shown. Asterisks indicate areas populated solely by bladder cancer cells.
Peter J. Boström (470005) +7 more
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Decorin binding protein compositions
, 1998 Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias.
Guo, Betty, Hook, Magnus
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Differential roles for small leucine-rich proteoglycans in bone formation
European Cells & Materials, 2003 This paper reviews our current state of knowledge of the roles the small leucine-rich proteoglycans (SLRPs) play in the formation of connective tissue and mineralised tissue matrices.
Waddington R. J. +3 more
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, 1991 1. The extracellular matrix (ECM) of rat skeletal muscle contains several proteoglycans (PGs). The more abundant correspond to a chondroitin/dermatan sulfate PG or decorin.2. Decorin isolated from rat skeletal muscle ECM has a smaller molecular size than
BRANDAN, E, ANDRADE, W
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Pivotal role for decorin in angiogenesis
, 2015 Angiogenesis, the formation of new blood vessels from preexisting vessels, is a highly complex process. It is regulated in a finely-tuned manner by numerous molecules including not only soluble growth factors such as vascular endothelial growth factor ...
Järveläinen, Hannu +2 more
core +1 more source
An antimetastatic role for decorin in breast cancer
, 2008 Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase family and attenuates their signaling, leading to growth inhibition. We investigated the effects of decorin on the growth of
Matteo Fassan +17 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要： 【目的】 阐明ＢＭＰ２是否参与了Ｄｅｃｏｒｉｎ诱导的血管平滑肌细胞（ＶＳＭＣ）钙化。【方法】 本研究采用人血管平滑肌细胞钙化体外模型，用腺病毒载体过表达Ｄｅｃｏｒｉｎ，检测骨相关蛋白ＢＭＰ２、Ｍｓｘ２、Ｏｓｔｅｒｉｘ的表达和细胞钙化程度。观察抑制或增加ＢＭＰ２信号对Ｄｅｃｏｒｉｎ诱导的血管平滑肌细胞钙化和Ｍｓｘ２、Ｏｓｔｅｒｉｘ表达的影响。【结果】Ｄｅｃｏｒｉｎ能促进人血管平滑肌细胞钙化，同时上调ＢＭＰ２、Ｍｓｘ２、Ｏｓｔｅｒｉｘ的表达水平。抑制ＢＭＰ２能减轻Ｄｅｃｏｒｉｎ诱导的细胞钙化 ...
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