Results 101 to 110 of about 23,792 (227)

Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties. [PDF]

, 2014
IntroductionMultipotent progenitor populations exist within the tendon proper and peritenon of the Achilles tendon. Progenitor populations derived from the tendon proper and peritenon are enriched with distinct cell types that are distinguished by ...
Adams, Sheila M, Birk, David E, Mienaltowski, Michael J   +2 more
core   +1 more source

Assessment of two minimally invasive methodologies for sex identification in the European eel, Anguilla anguilla

Journal of Fish Biology, EarlyView.
Abstract Sex is an important driver of variation in behaviour, ecology and physiology. Sex identification in the Critically Endangered European eel (Anguilla anguilla) currently requires fish sacrifice, or the use of morphological differences such as body length, which can be inaccurate in certain habitats and at intermediate body lengths.
Michael J. Williamson, Jack A. Brand, Kevin Hopkins, Luke O'Connor, Matthew W. Perkins, Christopher Sergeant, Simon Spiro, Taina Strike, Jessica Whinfield, Rosie S. Williams, Ethan Wrigglesworth, Rosalind M. Wright, Adam T. Piper   +12 more
wiley   +1 more source

Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury

Molecules, 2020
Search for new cardioprotective therapies is of great importance since no cardioprotective drugs are available on the market. In line with this need, several natural biomolecules have been extensively tested for their potential cardioprotective effects ...
Renáta Gáspár, Kamilla Gömöri, Bernadett Kiss, Ágnes Szántai, János Pálóczi, Zoltán V. Varga, Judit Pipis, Barnabás Váradi, Bence Ágg, Tamás Csont, Péter Ferdinandy, Monika Barteková, Anikó Görbe   +12 more
doaj   +1 more source

The matricellular functions of small leucine-rich proteoglycans (SLRPs) [PDF]

, 2009
The small leucine-rich proteoglycans (SLRPs) are biologically active components of the extracellular matrix (ECM), consisting of a protein core with leucine rich-repeat (LRR) motifs covalently linked to glycosaminoglycan (GAG) side chains.
Rosetta Merline, Roland M. Schaefer, Liliana Schaefer   +2 more
core   +1 more source

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, EarlyView.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Tenocytic induction of stem cells from bone marrow on polymeric microparticles for a new concept of tendon regenerative prosthesis [PDF]

, 2015
A new concept of a regenerative and resorbable prosthesis for tendon and ligament has been developed. The prosthesis consists of a poly-lactide acid (PLA) braid, microparticles in its interior serving as cell carriers, and a surface non-adherent coating.
Andrades-Gomez, Jose Antonio, Araque-Monrós, Mª Carmen, Becerra-Ratia, Jose, Claros, Silvia, Gil-Santos, Luis, Monleón-Pradas, Manuel, Más-Estellés, Jorge, Rodríguez-Losada, Noela   +7 more
core  

Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers [PDF]

, 2014
[Image: see text] TGF-β1, -β2, and -β3 are small, secreted signaling proteins. They share 71–80% sequence identity and signal through the same receptors, yet the isoform-specific null mice have distinctive phenotypes and are inviable.
Andrew P. Hinck, Archer S. J., Archer S. J., Baardsnes J., Baker S. M., Bandyopadhyay B., Biernacka A., Bocharov E. V., Bocharov E. V., Cheifetz S., Daopin S., Deep S., Delaglio F., Eghbalnia H. R., Freedberg D. I., Gato A., Goddard T. D., Groppe J., Grutter C., Grzesiek S., Grzesiek S., Hall B. E., Hart P. J., Hinck A. P., Hinck A. P., Huang T., Kay L. E., Kay L. E., Kulkarni A. B., Liu Q., Loeys B. L., Lopez-Casillas F., Marley J., Massague J., Massague J., Massague J., Mendoza V., Mittl P. R., Moustakas A., Munoz V., Munoz V., Nilsen-Hamilton M., Pellaud J., Proetzel G., Qian S. W., Radaev S., Sanford L. P., Schlunegger M. P., Schor S. L., Seth L. Schor, Shah M., Shi Y., Shull M. M., Tao Huang, Taya Y., Tudela C., Wittekind M., Wrana J. L., Wrana J. L., Yang L. T., Zou Z., Zuniga J. E.   +61 more
core   +2 more sources

Detrimental Effect of Low‐Magnitude High‐Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment

JOR SPINE, Volume 9, Issue 2, June 2026.
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen, Felizitas Figel, Franziska Widmayer, Morten Vogt, Maria Ahrens, Hans‐Joachim Wilke, Anita Ignatius, Melanie Haffner‐Luntzer, Cornelia Neidlinger‐Wilke, Graciosa Quelhas Teixeira   +9 more
wiley   +1 more source

Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion [PDF]

, 2014
Cancer progression is characterized by a complex reciprocity between neoplastic epithelium and adjacent stromal cells. In ductal carcinoma in situ (DCIS) of the breast, both reduced stromal decorin expression and myxoid stroma are correlated with ...
Bracke, Marc, Braems, Geert, Cocquyt, Veronique, De Vlieghere, Elly, De Wever, Olivier, Denys, Hannelore, Lambein, Kathleen, Libbrecht, Louis, LIMAME, RIDHA, Van Bockstal, Mieke, Van den Broecke, Rudy, Van Gele, Mireille   +11 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, Volume 20, Issue 5, Page 1253-1269, May 2026.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source