Results 121 to 130 of about 23,792 (227)

Novel Non‐Invasive Treatment for Canine Corneal Ulcers: Application of New Extracellular Matrix‐Based Sticky Sealants

open access: yesVeterinary Ophthalmology, Volume 29, Issue 3, May 2026.
ABSTRACT Objective To evaluate the clinical efficacy of a newly developed adhesive tissue sealant, gelatinized cornea‐derived decellularized extracellular matrix (Cod‐ECM) for the treatment of stromal ulcers in dogs. Animal Studied This study included 60 eyes of 56 dogs diagnosed with stromal ulcerative keratitis, limited to corneal ulcers involving ...
Su‐Jung Yang   +4 more
wiley   +1 more source

Decorin Suppresses Prostate Tumor Growth through Inhibition of Epidermal Growth Factor and Androgen Receptor Pathways

open access: yesNeoplasia: An International Journal for Oncology Research, 2009
Epidermal growth factor receptor (EGFR) and androgen receptor (AR) pathways play pivotal roles in prostate cancer progression. Therefore, agents with dual-targeting ability may have important therapeutic potential.
Yunping Hu   +8 more
doaj   +1 more source

Recombinant Decorin Glycoforms [PDF]

open access: yesJournal of Biological Chemistry, 1996
Priya Ramamurthy   +2 more
openaire   +1 more source

Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]

open access: yes, 2010
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou   +3 more
core   +1 more source

3Ds: decorin, discordance, and diamniotic dichorionic twins

open access: yesClinical and Experimental Obstetrics & Gynecology, 2017
aullimary Investigation: The cause of discordance in dichorionic diamniotic (DD) twins is still unknown. The authors aimed to compare decorin (DCN) and oxidative/antioxidative state levels between the placentas of discordant and concordant twins.Prospective study of 43 spontaneous DD twin pregnancies included and placentas samples taken from each twin ...
Ergin, M.   +6 more
openaire   +3 more sources

Lentiviral-Encoded shRNA Silencing of Proteoglycan Decorin Enhances Tendon Repair and Regeneration within a Rat Model

open access: yesCell Transplantation, 2013
Injured tendons often heal with scar tissue formation, resulting in uniformly smaller collagen fibrils and poor mechanical properties. The small leucine-rich proteoglycan decorin is well known to regulate fusion of collagen fibrils.
Ping Lu   +8 more
doaj   +1 more source

Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature. [PDF]

open access: yes, 2018
Regulation of autophagy by proteolytically cleaved fragments of heparan sulfate proteoglycans is a novel and current research focus in tumor biology. Endorepellin is the C-terminal angiostatic fragment of the heparan sulfate proteoglycan perlecan and ...
Andreuzzi, Eva   +5 more
core   +1 more source

Increased expression of decorin in experimental hydronephrosis

open access: yesKidney International, 1997
Transforming growth factor (TGF)-beta1 is a potential mediator of tubulointerstitial (TI) fibrosis in the rat unilateral ureteral obstruction (UUO) model. Decorin is a protein composed of a core protein and a chondroitin sulfate side chain and is capable of inactivating TGF-beta.
Diamond, Jonathan R.   +3 more
openaire   +2 more sources

Potential use of decorin in preventing cerebral vasospasm through the inhibition of transforming growth factor-beta activity: Insights from an experimental rabbit subarachnoid hemorrhage model

open access: yesWorld Neurosurgery: X
Objective: The development of vasospasm after subarachnoid hemorrhage (SAH) is a major cause of death and disability. It leads to structural changes such as smooth muscle and myofibroblast proliferation, necrosis, intimal hyperplasia, and vascular ...
Betul Yaman   +7 more
doaj   +1 more source

Role of Decorin Core Protein in Collagen Organisation in Congenital Stromal Corneal Dystrophy (CSCD).

open access: yesPLoS ONE, 2016
The role of Decorin in organising the extracellular matrix was examined in normal human corneas and in corneas from patients with Congenital Stromal Corneal Dystrophy (CSCD).
Christina S Kamma-Lorger   +10 more
doaj   +1 more source

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