Results 111 to 120 of about 18,800 (200)

Citral inibe a inflamação aguda e nocicepção em camundongos: o papel dos receptores TLR4 e TLR2/DECTINA-1 [PDF]

open access: yes, 2015
TCC(graduação) - Universidade Federal de Santa Catarina. Araranguá. Fisioterapia.Citral (3,7-dimethyl-2,6-octadienal), um monoterpeno de cadeia aberta e principal componente bioativo do capim limão, apresenta diferentes propriedades farmacológicas, tais ...
Gonçalves, Elaine Cristina Dalazen
core  

Microbial ligand costimulation drives neutrophilic steroid-refractory asthma [PDF]

open access: yes, 2015
Asthma is a heterogeneous disease whose etiology is poorly understood but is likely to involve innate responses to inhaled microbial components that are found in allergens.
Brombacher, Frank   +16 more
core   +7 more sources

Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia.

open access: yesPLoS ONE, 2016
BackgroundPatients with acute myeloid leukemia (AML) who undergo induction chemotherapy are at high risk for invasive fungal disease (IFD). Dectin-1, a C-type lectin family member represents one of the most important pattern recognition receptors of the ...
Mike Fischer   +8 more
doaj   +1 more source

Immunogenetic profiling to predict risk of invasive fungal diseases : where are we now? [PDF]

open access: yes, 2011
Invasive fungal diseases remain nowadays life-threatening conditions affecting multiple clinical settings. The onset of these diseases is dependent on numerous factors, of which the "immunocompromised" phenotype of the patients is the more often ...
Aversa, Franco   +6 more
core   +1 more source

Inhibition of Dectin-1 on Dendritic Cells Prevents Maturation and Prolongs Murine Islet Allograft Survival

open access: yesJournal of Inflammation Research, 2021
Ao Ren,1– 3 Zhongqiu Li,1– 3 Xuzhi Zhang,1– 3 Ronghai Deng,1– 3 Yi Ma1– 3 1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial ...
Ren A, Li Z, Zhang X, Deng R, Ma Y
doaj  

Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis [PDF]

open access: yes, 2017
Acknowledgements: The authors would like to acknowledge Fraser P. Coxon and Ian Ganley for providing LC3-GFP-mCherry BMDMs. M.S.G. was supported by an FEMS research grant and F.L.v.d.V.
Alonso, M Fernanda   +8 more
core   +2 more sources

Zymosan treatment of mouse mast cells enhances dectin-1 expression and induces dectin-1-dependent reactive oxygen species (ROS) generation

open access: yesImmunobiology, 2009
Dectin-1 is a major beta-glucan receptor expressed in the innate immune cells such as macrophages, neutrophils and dendritic cells. It can mediate pro-inflammatory mediator release and other cellular responses such as phagocytosis and respiratory burst in response to pathogens. Mast cells are sentinel cells of the immune system found in greater numbers
Zhan, Yang, Jean S, Marshall
openaire   +2 more sources

Targeting CBLB as a potential therapeutic approach for disseminated candidiasis [PDF]

open access: yes, 2016
We thank J.M. Penninger (University of Toronto) for providing Cblb−/− mice, Y. Iwakura (Tokyo University of Science) for providing Clec4n−/− mice, S. Lipkowitz (National Cancer Institute, US National Institutes of Health) for providing Cblb constructs, X.
Brown, Gordon D.   +14 more
core   +1 more source

The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages

open access: yesFrontiers in Immunology, 2018
Autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a primary immunodeficiency caused by mutations in the autoimmune regulator gene (AIRE). Patients with AIRE mutations are susceptible to Candida albicans infection and present with
Jose Antonio Tavares de Albuquerque   +21 more
doaj   +1 more source

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

open access: yesPLoS Biology, 2018
The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain incompletely understood. Here, we report that soluble egg antigen (SEA) from Schistosoma mansoni, which
Maria M M Kaisar   +12 more
doaj   +1 more source

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