Results 101 to 110 of about 18,918 (210)

Dectin-1 binding to annexins on apoptotic cells induces peripheral immune tolerance via NADPH oxidase-2

open access: yes, 2019
Summary Uptake of apoptotic cells (ACs) by dendritic cells (DCs) and induction of a tolerogenic DC phenotype is an important mechanism for establishing peripheral tolerance to self-antigens.
Bode, K.   +9 more
core   +1 more source

Glycans from Fasciola hepatica modulate the host immune response and TLR-Induced maturation of dendritic cells [PDF]

open access: yes, 2015
Helminths express various carbohydrate-containing glycoconjugates on their surface, and they release glycan-rich excretion/secretion products that can be very important in their life cycles, infection and pathology. Recent evidence suggests that parasite
Brossard, Natalie   +8 more
core   +4 more sources

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

open access: yesCancer Nexus, Volume 2, Issue 2, April 2026.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han   +5 more
wiley   +1 more source

Soluble Dectin-1 as a tool to detect β-glucans

open access: yesJournal of Immunological Methods, 2006
Beta-glucans are structural components of fungal cell walls which are involved in the immune recognition of fungal pathogens and possess beneficial immunomodulatory activities in isolated form. Here we have developed a soluble chimeric form of the major mammalian beta-glucan receptor, Dectin-1, and demonstrate its application for the detection and ...
Graham, Lisa   +7 more
openaire   +3 more sources

Comparative Effect of Maitake Pro4x with Chemotherapy Breast Cancer Treatment [PDF]

open access: yes, 2017
Conventional treatments for breast cancer involve surgery followed by radiation and hormonal therapy and/or chemotherapy. Some of these treatments have toxic side effects.
Aguilera Braico, Diego Máximo   +3 more
core   +1 more source

Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNγ- CD4+ T cell expansion through an IL-23 and TGF-β-dependent mechanism in patients with MDR-TB tuberculosis [PDF]

open access: yes, 2016
We have previously reported that T cells from patients with multidrug-resistant tuberculosis (MDR-TB) express high levels of IL-17 in response to the MDR strain M(Haarlem family) of Mycobacterium tuberculosis (M.tuberculosis).
Balboa, Luciana   +13 more
core   +2 more sources

TLR-4 Cooperates with Dectin-1 and Mannose Receptor to Expand Th17 and Tc17 Cells Induced by Paracoccidioides brasiliensis Stimulated Dendritic Cells

open access: yesFrontiers in Microbiology, 2015
The concomitant use of diverse Pattern Recognition Receptors (PRRs) by innate immune cells can result in synergistic or inhibitory activities that profoundly influence anti-microbial immunity.
Vera Lucia Garcia Calich   +4 more
doaj   +1 more source

Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis [PDF]

open access: yes, 2017
Acknowledgements: The authors would like to acknowledge Fraser P. Coxon and Ian Ganley for providing LC3-GFP-mCherry BMDMs. M.S.G. was supported by an FEMS research grant and F.L.v.d.V.
Alonso, M Fernanda   +8 more
core   +2 more sources

Role of Bacterial Lipopolysaccharide in Enhancing Host Immune Response to Candida albicans

open access: yesClinical and Developmental Immunology, 2013
Human infections involving yeast of the genus Candida often occur in the presence of bacteria, and, as such, it is important to understand how these bacteria influence innate host immunity towards Candida.
Helen Rogers   +4 more
doaj   +1 more source

C-type lectin-like receptors of the dectin-1 cluster : ligands and signaling pathways [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Brown, Gordon D   +2 more
core   +1 more source

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