Results 81 to 90 of about 21,245,874 (166)

The Core Fucose on an IgG Antibody is an Endogenous Ligand of Dectin‐1

Angewandte Chemie International Edition, 2019
AbstractThe core fucose, a major modification of N‐glycans, is implicated in immune regulation, such as the attenuation of the antibody‐dependent cell‐mediated cytotoxicity of antibody drugs and the inhibition of anti‐tumor responses via the promotion of PD‐1 expression on T cells.
Manabe, Yoshiyuki, Marchetti, Roberta, Takakura, Yohei, Nagasaki, Masahiro, Nihei, Wataru, Takebe, Tomoyuki, Tanaka, Katsunori, Kabayama, Kazuya, Chiodo, Fabrizio, Hanashima, Shinya, Kamada, Yoshihiro, Miyoshi, Eiji, Dulal, Hari Prasad, Yamaguchi, Yoshiki, Adachi, Yoshiyuki, Ohno, Naohito, Tanaka, Hiroshi, Silipo, Alba, Fukase, Koichi, Molinaro, Antonio   +19 more
openaire   +6 more sources

Dectin-1 deficiency does not affect atherosclerosis development in mice

, 2015
ObjectiveRecent data suggest the involvement of dectin-1 in atherosclerosis through regulation of local reactive oxygen species production. The aim of the current study was to assess the effect of dectin-1 deficiency on atherosclerotic plaque development.
Gijbels, Marion J. J., van den Berg, Timo K., Gijbels, Marion J.J., Kraal, Georg, van der Velden, Saskia, Heinsbroek, Sigrid E. M., de Winther, Menno P. J., Szilagyi, Katka, de Winther, Menno P.J., Heinsbroek, Sigrid E.M.   +9 more
core   +1 more source

Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases [PDF]

, 2018
Patients with cystic fibrosis (CF) experience chronic or recurrent bacterial and fungal lung infections. Many patients with CF cannot effectively clear Aspergillus from their lungs.
Taylor, Philip R., Forton, Julian, Aiysha Thompson, Herrick, Sarah, Benny, A, Orr, SJ; id_orcid, Thompson, A, Lewis, NA, Selinda J. Orr, Herrick, S, Julian Forton, McGreal, Eamon P., Philip R. Taylor, Stott, Matthew, Stott, M, McGreal, EP, Sarah Herrick, Taylor, PR, Griffiths, JS, Natalie A. Lewis, James S. Griffiths, Thompson, Aiysha, Forton, J, Eamon P. McGreal, Griffiths, James S., Benny, Ankita, Herrick, Sarah; id_orcid, Matthew Stott, Orr, Selinda J., Ankita Benny, Lewis, Natalie A.   +30 more
core   +1 more source

Dectin-1 Deficiency and Mucocutaneous Fungal Infections [PDF]

New England Journal of Medicine, 2010
László, Maródi, Melinda, Erdös
openaire   +2 more sources

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Data_Sheet_1_Interleukin-33 Contributes to the Induction of Th9 Cells and Antitumor Efficacy by Dectin-1-Activated Dendritic Cells.PDF

, 2018
We recently discovered that dectin-1-activated dendritic cells (DCs) drive potent T helper (Th) 9 cell responses and antitumor immunity. However, the underlying mechanisms need to be further defined.
Siqing Wang (5572508), Qing Yi (495197), Jintong Chen (5572493), Yinghua Zhao (619439), Alison Wang (5572502), Sujun Gao (530382), Huanfa Yi (5572505), Yiming Wang (163598), Dongjiao Wang (5572499), Yuxue Jiang (5572496), Rui Gu (361957)   +10 more
core   +1 more source

Table_1_Interleukin-33 Contributes to the Induction of Th9 Cells and Antitumor Efficacy by Dectin-1-Activated Dendritic Cells.XLS

, 2018
We recently discovered that dectin-1-activated dendritic cells (DCs) drive potent T helper (Th) 9 cell responses and antitumor immunity. However, the underlying mechanisms need to be further defined.
Siqing Wang (5572508), Qing Yi (495197), Jintong Chen (5572493), Yinghua Zhao (619439), Alison Wang (5572502), Sujun Gao (530382), Huanfa Yi (5572505), Yiming Wang (163598), Dongjiao Wang (5572499), Yuxue Jiang (5572496), Rui Gu (361957)   +10 more
core   +1 more source

Dectin-1 embraces Candida glabrata [PDF]

Virulence, 2017
openaire   +2 more sources

Dectin-1 signaling promotes Galectin-3 shedding and expansion of immunosuppressive CD71+ erythroid cells in breast cancer. [PDF]

Oncoimmunology
Azimi A, Rahmati A, Shahbaz S, Elahi Z, Zahiriabyaneh A, Cao J, Padua EL, Church C, Alimo ET, Lavasanifar A, Walker J, Elahi S.   +11 more
europepmc   +1 more source

Dectin-1 : receptor internalisation, trafficking and biological effects in macrophages

, 2004
In host defence, pattern recognition plays an essential role by enabling the immune system to discriminate self from pathogenic non-self. Pattern recognition is mediated by leukocyte expressed pattern recognition molecules (PRMs), which recognise ...
Gordon, Siamon, Herre, Jürgen
core