Results 71 to 80 of about 21,245,874 (166)

Soluble Dectin-1 as a tool to detect β-glucans

Journal of Immunological Methods, 2006
Beta-glucans are structural components of fungal cell walls which are involved in the immune recognition of fungal pathogens and possess beneficial immunomodulatory activities in isolated form. Here we have developed a soluble chimeric form of the major mammalian beta-glucan receptor, Dectin-1, and demonstrate its application for the detection and ...
Graham, Lisa, Tsoni, S. Vicky, Willment, Janet A., Williams, David L., Taylor, Philip R., Gordon, Siamon, Dennehy, Kevin, Brown, Gordon D.   +7 more
openaire   +3 more sources

Malassezia restricta‐Derived Extracellular Vesicles Drive Ovarian Cancer Progression Through JAK2/STAT3‐Mediated M2 Macrophage Polarisation

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
Schematic diagram of the potential mechanism by which Malassezia restricta promote ovarian cancer progression. Malassezia restricta‐derived extracellular vesicles promoted epithelial ovarian cancer progression by inducing M2 macrophage polarisation via activation of the JAK2/STAT3 signalling pathway.
Ying Jiang, Fen Wei, Qingling Yang, Xue Wu, Qifa Huang, Ang Dai, Qi Chen, Tingtao Chen   +7 more
wiley   +1 more source

Dectin-3 deficiency does not impact pulmonary leukocyte recruitment during immune response to C. neoformans infection.

, 2017
C57BL/6 (WT) and Dectin-3 KO mice were infected via intranasal inoculation with C. neoformans strain H99. Lungs were excised at days 7 and 14 post-inoculation and pulmonary infiltrates analyzed by flow cytometry.
Karen L. Wozniak (229721), Chrissy M. Leopold Wager (614801), Floyd L. Wormley Jr. (220899), Althea Campuzano (3687070), Natalia Castro-Lopez (3687067)   +4 more
core   +1 more source

Beta‐Glucan: A Macrophage Differentiation Modulator That Accelerates the Wound Healing Response

International Wound Journal, Volume 23, Issue 6, June 2026.
ABSTRACT Beta Glucans (β‐glucans) are naturally occurring polysaccharides that have positive effects on healing in acute and chronic wounds. This study aimed to identify how β‐glucans modulate macrophage polarisation and inflammation to aid the healing response.
Stuart James Mills, Cyan Sylvester, Darryl Reed, Tony Charara, Allison June Cowin   +4 more
wiley   +1 more source

Image_1_Intestinal Macrophages Balance Inflammatory Expression Profiles via Vitamin A and Dectin-1-Mediated Signaling.JPEG

, 2020
Tissue resident intestinal macrophages are known to exhibit an anti-inflammatory phenotype and produce little pro-inflammatory cytokines upon TLR ligation, allowing symbiotic co-existence with the intestinal microbiota. However, upon acute events such as
Jan Van den Bossche (7571246), Wouter J. de Jonge (7571258), Kyra E. de Goede (8647809), Sanne G. S. Verberk (8647812), Reina E. Mebius (3373049), Martje N. Erkelens (8115689), Marieke R. Beijer (8647806), Tanja Konijn (3373055), Rosalie Molenaar (8647803), Joke M. M. den Haan (7500083), Gera Goverse (5264510)   +10 more
core   +1 more source

Image_2_Intestinal Macrophages Balance Inflammatory Expression Profiles via Vitamin A and Dectin-1-Mediated Signaling.JPEG

, 2020
Tissue resident intestinal macrophages are known to exhibit an anti-inflammatory phenotype and produce little pro-inflammatory cytokines upon TLR ligation, allowing symbiotic co-existence with the intestinal microbiota. However, upon acute events such as
Jan Van den Bossche (7571246), Wouter J. de Jonge (7571258), Kyra E. de Goede (8647809), Sanne G. S. Verberk (8647812), Reina E. Mebius (3373049), Martje N. Erkelens (8115689), Marieke R. Beijer (8647806), Tanja Konijn (3373055), Rosalie Molenaar (8647803), Joke M. M. den Haan (7500083), Gera Goverse (5264510)   +10 more
core   +1 more source

Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut.

, 2016
Interactions between commensal fungi and gut immune system are critical for establishing colonic homeostasis. Here we found that mice deficient in Dectin-3 (Clec4d-/-), a C-type lectin receptor that senses fungal infection, were more susceptible to ...
Deng Pan (47215), Tingting Wang, Xin Lin, Xin Lin (149944), Deng Pan, Xueqiang Zhao, Tingting Wang (123983), Zhicheng Zhou, Changying Jiang (2823584), Yun You (2158558), Xueqiang Zhao (2823587), Zhicheng Zhou (348854), Changying Jiang, Yun You   +13 more
core   +1 more source

Image_4_Intestinal Macrophages Balance Inflammatory Expression Profiles via Vitamin A and Dectin-1-Mediated Signaling.JPEG

, 2020
Tissue resident intestinal macrophages are known to exhibit an anti-inflammatory phenotype and produce little pro-inflammatory cytokines upon TLR ligation, allowing symbiotic co-existence with the intestinal microbiota. However, upon acute events such as
Jan Van den Bossche (7571246), Wouter J. de Jonge (7571258), Kyra E. de Goede (8647809), Sanne G. S. Verberk (8647812), Reina E. Mebius (3373049), Martje N. Erkelens (8115689), Marieke R. Beijer (8647806), Tanja Konijn (3373055), Rosalie Molenaar (8647803), Joke M. M. den Haan (7500083), Gera Goverse (5264510)   +10 more
core   +1 more source

Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis. [PDF]

, 2010
Contains fulltext : 88551.pdf (Publisher’s version ) (Open Access)INTRODUCTION: Dectin-1, a pattern recognition receptor expressed by the innate immune system, is known to be a major receptor inducing Th17-type adaptive immune responses
Leo AB Joosten, Riel, P.L.C.M. van, Wim van den Berg, Stienstra, R., Berg, W.B. van den, Plantinga, T.S., Joosten, L.A.B., Rinke Stienstra, Netea, M.G., Fransen, J., Nozomi Takahashi, Takahashi, N., Piet L van Riel, Theo S Plantinga, Jaap Fransen, Mihai G Netea   +15 more
core   +1 more source

Citral inibe a inflamação aguda e nocicepção em camundongos: o papel dos receptores TLR4 e TLR2/DECTINA-1 [PDF]

, 2015
TCC(graduação) - Universidade Federal de Santa Catarina. Araranguá. Fisioterapia.Citral (3,7-dimethyl-2,6-octadienal), um monoterpeno de cadeia aberta e principal componente bioativo do capim limão, apresenta diferentes propriedades farmacológicas, tais ...
Gonçalves, Elaine Cristina Dalazen
core