Results 121 to 130 of about 21,245,874 (166)

Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing. [PDF]

Proc Natl Acad Sci U S A
Li XX, Fung JN, Clark RJ, Lee JD, Woodruff TM.   +4 more
europepmc   +1 more source

Dectin-1/SYK Activation Induces Antimicrobial Peptide and Negative Regulator of NF-κB Signaling in Human Oral Epithelial Cells. [PDF]

In Vivo
Inomata M, Abe M, Kawase Y, Hayashi T, Amano S, Sakagami H.   +5 more
europepmc   +1 more source

Dectin-1 aggravates neutrophil inflammation through caspase-11/4-mediated macrophage pyroptosis in asthma. [PDF]

Respir Res
Cai R, Gong X, Li X, Jiang Y, Deng S, Tang J, Ge H, Wu C, Tang H, Wang G, Xie L, Chen X, Hu X, Feng J.   +13 more
europepmc   +1 more source

Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks. [PDF]

Sci Rep
Cheng QJ, Farrell K, Fenn J, Ma Z, Makanani SK, Siemsen J.   +5 more
europepmc   +1 more source

Neem leaf glycoprotein binding to Dectin-1 receptors on dendritic cell induces type-1 immunity through CARD9 mediated intracellular signal to NFκB. [PDF]

Cell Commun Signal
Ganguly N, Das T, Bhuniya A, Guha I, Chakravarti M, Dhar S, Sarkar A, Bera S, Dhar J, Dasgupta S, Saha A, Ghosh T, Das J, Sk UH, Banerjee S, Laskar S, Bose A, Baral R.   +17 more
europepmc   +1 more source

Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. [PDF]

Nat Immunol
Theobald H, Bejarano DA, Katzmarski N, Haub J, Schulte-Schrepping J, Yu J, Bassler K, Ament AL, Osei-Sarpong C, Piattini F, Vornholz L, T'Jonck W, Györfi AH, Hayer H, Yu X, Sheoran S, Al Jawazneh A, Chakarov S, Haendler K, Brown GD, Williams DL, Bosurgi L, Distler JHW, Ginhoux F, Ruland J, Beyer MD, Greter M, Bain CC, Vazquez-Armendariz AI, Kopf M, Schultze JL, Schlitzer A.   +31 more
europepmc   +1 more source

Arabinoxylan activates Dectin‐1 and modulates particulate β‐glucan‐induced Dectin‐1 activation

Molecular Nutrition & Food Research, 2015
ScopeArabinoxylan is one of the most commonly consumed dietary fiber. Immunomodulation by arabinoxylan is documented but the mechanisms by which these immune‐effects are accomplished are unknown.Methods and resultsBy applying reporter cell lines for Toll‐like receptors (TLRs) and Dectin‐1, we demonstrated that arabinoxylan interacts with Dectin‐1 ...
Sahasrabudhe, Neha M., Schols, Henk A., Faas, Marijke M., de Vos, Paul   +3 more
openaire   +4 more sources

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Emerging roles of Dectin-1 in noninfectious settings and in the CNS

Trends in Immunology, 2021
Dectin-1 is a C-type lectin receptor (CLR) expressed on the surface of various mammalian myeloid cells. Dectin-1 recognizes β-glucans and elicits antifungal proinflammatory immune responses. Recent studies have begun to examine the biology of Dectin-1 in previously less explored settings, such as homeostasis, sterile inflammation, and in the central ...
M Elizabeth Deerhake, Mari L Shinohara
exaly   +3 more sources

A critical role of Dectin-1 in hypersensitivity pneumonitis

Inflammation Research, 2015
Hypersensitivity pneumonitis (HP) is a pulmonary disease caused by repeated exposure to various aspiration antigens, including bacteria and fungi. Although TLRs are known to be required for the generation of HP triggered by bacteria, the significance of fungal receptors remains unclear. The present study aimed to investigate whether Dectin-1 and Dectin-
Toshiki Yabe-Wada, Kazushi Anzawa, Takashi Mochizuki   +2 more
exaly   +3 more sources

Identification of the Porcine C-type lectin dectin-1

Veterinary Immunology and Immunopathology, 2009
Beta-glucans are conserved glucose polymers found in the cell walls of plants, fungi, yeasts and bacteria. They have a backbone of beta-(1-3)-linked glucose units with beta-(1-6)-glucan-linkages. Although a number of receptors are thought to play a role in mediating the biological response to beta-glucans, dectin-1, a C-type lectin, was described as ...
Eva, Sonck, Edith, Stuyven, Bruno, Goddeeris, Eric, Cox   +3 more
openaire   +3 more sources