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2012
Natural killer (NK) cell receptors belong to two unrelated, but functionally analogous gene families: the immunoglobulin superfamily, situated in the leukocyte receptor complex (LRC) and the C-type lectin receptors (CLRs) superfamily, located in the natural killer gene complex (NKC). Wong et al.
Rajesh K. Gupta, G. S. Gupta
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Natural killer (NK) cell receptors belong to two unrelated, but functionally analogous gene families: the immunoglobulin superfamily, situated in the leukocyte receptor complex (LRC) and the C-type lectin receptors (CLRs) superfamily, located in the natural killer gene complex (NKC). Wong et al.
Rajesh K. Gupta, G. S. Gupta
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Annals of the New York Academy of Sciences, 2009
beta-Glucans are naturally occurring carbohydrates that possess immune-modulating activities, but their mechanisms of action are largely unknown. Recent discoveries, however, including identification of beta-glucan receptors, such as dectin-1, have started to shed some light on the mechanisms underlying the properties of these carbohydrates.
S Vicky, Tsoni, Gordon D, Brown
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beta-Glucans are naturally occurring carbohydrates that possess immune-modulating activities, but their mechanisms of action are largely unknown. Recent discoveries, however, including identification of beta-glucan receptors, such as dectin-1, have started to shed some light on the mechanisms underlying the properties of these carbohydrates.
S Vicky, Tsoni, Gordon D, Brown
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Variation in the Yak Dectin-1 Gene ( CLEC7A )
DNA and Cell Biology, 2011C-type lectin domain family 7, member A (CLEC7A, dectin-1) plays an important role in antifungal immunity and belongs to the family of C-type lectin receptors. Variation in the extended exon 4-6 region of the yak dectin-1 gene (CLEC7A), which encodes the β-glucan recognition domain, was investigated using polymerase chain reaction-single strand ...
Guo, Yang +4 more
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Dectin-1: unique appetite for yeast
Blood, 2004Comment on Herre et al, page [4038][1] Dectin-1 is a myeloid receptor involved in phagocytosis of fungal pathogens that uses a unique mechanism of internalization and cellular signaling. P hagocytosis of pathogens is a critically important activity of cells of the innate immune system.
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Dectin-1 (CLEC7A, BGR, CLECSF12)
2016Dectin-1 is the archetypical example of the C-type lectin receptor (CLR) family of pattern recognition receptors (PRRs). Expressed primarily by cells of the innate immune system, this receptor is best known for its role in antifungal immunity through its ability to recognise cell wall β-glucans.
Patawee Asamaphan +2 more
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Pilz-Beta-Glukane aktivieren die Immunantwort über verschiedene Rezeptoren, darunter C-Typ-Lektin-Rezeptoren (CLRs). Eine besondere Rolle spielt dabei Dectin-1. Frühere Studien deuteten darauf hin, dass der Dectin-1-Signalweg, der zur Interleukinproduktion führt, nur durch Hefepartikel aktiviert werden konnte, indem eine Immunsynapse gebildet wird. Die
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Dectin-1 limits allergic responses
Science, 2018Allergy Aberrant activation of pattern recognition receptors (PRRs) drives inflammation in autoimmune and allergic diseases. Gour et al. identified invertebrate tropomyosin from house dust mites and shrimp as a ligand for dectin-1. Dectin-1 is a PRR that recognizes fungal β-glucans in antifungal immune responses.
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Dectin-1 Acts as a Non-Classical Receptor of Ang II to Induce Cardiac Remodeling
Circulation Research, 2023Weijian Huang, Guang Liang
exaly

