Neem leaf glycoprotein binding to Dectin-1 receptors on dendritic cell induces type-1 immunity through CARD9 mediated intracellular signal to NFκB. [PDF]
Ganguly N +17 more
europepmc +1 more source
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. [PDF]
Theobald H +31 more
europepmc +1 more source
Role of Dectin-1 in immune response of macrophages induced by Fonsecaea monophora wild strain and melanin-deficient mutant strain. [PDF]
Zhong J +5 more
europepmc +1 more source
Extracellular vesicles from virulent P. brasiliensis induce TLR4 and dectin-1 expression in innate cells and promote enhanced Th1/Th17 response. [PDF]
Montanari Borges B +6 more
europepmc +1 more source
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Arabinoxylan activates Dectin‐1 and modulates particulate β‐glucan‐induced Dectin‐1 activation
Molecular Nutrition & Food Research, 2015ScopeArabinoxylan is one of the most commonly consumed dietary fiber. Immunomodulation by arabinoxylan is documented but the mechanisms by which these immune‐effects are accomplished are unknown.Methods and resultsBy applying reporter cell lines for Toll‐like receptors (TLRs) and Dectin‐1, we demonstrated that arabinoxylan interacts with Dectin‐1 ...
Sahasrabudhe, Neha M. +3 more
openaire +3 more sources
Dectin-1 escape by fungal dimorphism
Trends in Immunology, 2005Candida albicans, a medically important fungus, exists primarily as yeast and filamentous forms. Its cell wall is rich in beta-glucans, which are recognized by a lectin-like innate immune receptor, Dectin-1. A recent study shows that exposure of glucan, by yeasts but not filaments, determines Dectin-1-dependent uptake by macrophages, and thus ...
Heinsbroek, Sigrid E. M. +2 more
openaire +3 more sources
β‐Glucans are naturally occurring carbohydrates that possess immune‐modulating activities, but their mechanisms of action are largely unknown. Recent discoveries, however, including identification of β‐glucan receptors, such as dectin‐1, have started to shed some light on the mechanisms underlying the properties of these carbohydrates.
S. Vicky Tsoni, Gordon D. Brown
openaire +1 more source
Natural killer (NK) cell receptors belong to two unrelated, but functionally analogous gene families: the immunoglobulin superfamily, situated in the leukocyte receptor complex (LRC) and the C-type lectin receptors (CLRs) superfamily, located in the natural killer gene complex (NKC). Wong et al.
Rajesh K. Gupta, G. S. Gupta
openaire +1 more source
Fungal Recognition by TLR2 and Dectin-1
2008The innate immune system utilizes multiple receptors to recognize fungal pathogens, and the net inflammatory response is controlled by interactions between these receptors. Many fungi are recognized, at least in part, by Toll-like receptor 2 (TLR2) and Dectin-1.
Helen S, Goodridge, David M, Underhill
openaire +2 more sources

