Results 71 to 80 of about 18,800 (200)

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

Glycans from Fasciola hepatica modulate the host immune response and TLR-Induced maturation of dendritic cells [PDF]

, 2015
Helminths express various carbohydrate-containing glycoconjugates on their surface, and they release glycan-rich excretion/secretion products that can be very important in their life cycles, infection and pathology. Recent evidence suggests that parasite
Brossard, Natalie, Carmona, Carlos, Cervi, Laura Alejandra, Chiale, Carolina, Chiribao, Maria Laura, Freire, Teresa, Giacomini, Cecilia, Noya, Verónica, Rodriguez, Ernesto   +8 more
core   +4 more sources

Candida albicans colonization and dissemination from the murine gastrointestinal tract : the influence of morphology and Th17 immunity [PDF]

, 2014
This article is protected by copyright. All rights reserved. This work was supported by the Wellcome Trust (086558, 080088, 102705), a Wellcome Trust Strategic Award (097377) and a studentship from the University of Aberdeen. D.K.
Brown, Alistair J P, Brown, Gordon D, Chen, Kong, Drummond, Rebecca A, Gow, Neil A R, Kadosh, David, Kolls, Jay K, MacCallum, Donna M, Murray, Graeme I, Vautier, Simon   +9 more
core   +1 more source

Dectin-1 Mediates the Biological Effects of β-Glucans [PDF]

The Journal of Experimental Medicine, 2003
The ability of fungal-derived β-glucan particles to induce leukocyte activation and the production of inflammatory mediators, such as tumor necrosis factor (TNF)-α, is a well characterized phenomenon. Although efforts have been made to understand how these carbohydrate polymers exert their immunomodulatory effects, the receptors involved in generating ...
Brown, Gordon D., Herre, Jurgen, Williams, David L., Willment, Janet A., Marshall, Andrew S.J., Gordon, Siamon   +5 more
openaire   +4 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation.

PLoS ONE, 2012
We have re-investigated the role of the complement system and the non-opsonic pattern recognition receptors dectin-1 and dectin-2 in the recognition of fungal particles by inflammatory neutrophils, monocytes and macrophages.
Jacqueline U McDonald, Marcela Rosas, Gordon D Brown, Simon A Jones, Philip R Taylor   +4 more
doaj   +1 more source

Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNγ- CD4+ T cell expansion through an IL-23 and TGF-β-dependent mechanism in patients with MDR-TB tuberculosis [PDF]

, 2016
We have previously reported that T cells from patients with multidrug-resistant tuberculosis (MDR-TB) express high levels of IL-17 in response to the MDR strain M(Haarlem family) of Mycobacterium tuberculosis (M.tuberculosis).
Balboa, Luciana, Basile, Juan Ignacio, de la Barrera, Silvia Susana, García, A., Gonzalez Montaner, Pablo, Kviatcovsky, Denise, López, Beatriz, Monteserin, Johana, Palmero, Domingo, Ritacco, Gloria Viviana, Romero, María Mercedes, Sabio y García, Carmen Alejandra, Sasiain, María del Carmen, Vescovo, M.   +13 more
core   +2 more sources

Skin Mast Cells Contribute to Sporothrix schenckii Infection [PDF]

, 2020
Background: Sporothrix schenckii (S. schenckii), a dimorphic fungus, causes sporotrichosis. Mast cells (MCs) have been described to be involved in skin fungal infections. The role of MCs in cutaneous sporotrichosis remains largely unknown. Objectives:
Frischbutter, Stefan, Geng, Peng, Jiao, Qingqing, Li, Ruoyu, Luo, Ying, Maurer, Marcus, Scheffel, Jörg, Wang, Yuhan, Zhao, Zuotao   +8 more
core   +1 more source

Advances in Wine Yeast Autolysis: Biochemical and Molecular Mechanisms, and the Release of Organic Compounds in White and Sparkling Wines—An Updated Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos, Aniela Pinto Kempka   +1 more
wiley   +1 more source

Dectin-1/Syk signaling triggers neuroinflammation after ischemic stroke in mice

Journal of Neuroinflammation, 2020
Background Dendritic cell-associated C-type lectin-1 (Dectin-1) receptor has been reported to be involved in neuroinflammation in Alzheimer’s disease and traumatic brain injury.
Xin-Chun Ye, Qi Hao, Wei-Jing Ma, Qiu-Chen Zhao, Wei-Wei Wang, Han-Han Yin, Tao Zhang, Miao Wang, Kun Zan, Xin-Xin Yang, Zuo-Hui Zhang, Hong-Juan Shi, Jie Zu, Hafiz Khuram Raza, Xue-Ling Zhang, De-Qin Geng, Jin-Xia Hu, Gui-Yun Cui   +17 more
doaj   +1 more source