Results 81 to 90 of about 10,276 (160)

Role of Bacterial Lipopolysaccharide in Enhancing Host Immune Response to Candida albicans

Clinical and Developmental Immunology, 2013
Human infections involving yeast of the genus Candida often occur in the presence of bacteria, and, as such, it is important to understand how these bacteria influence innate host immunity towards Candida.
Helen Rogers, David W. Williams, Gui-Jie Feng, Michael A. O. Lewis, Xiao-Qing Wei   +4 more
doaj   +1 more source

Zymosan treatment of mouse mast cells enhances dectin-1 expression and induces dectin-1-dependent reactive oxygen species (ROS) generation

Immunobiology, 2009
Dectin-1 is a major beta-glucan receptor expressed in the innate immune cells such as macrophages, neutrophils and dendritic cells. It can mediate pro-inflammatory mediator release and other cellular responses such as phagocytosis and respiratory burst in response to pathogens. Mast cells are sentinel cells of the immune system found in greater numbers
Zhan, Yang, Jean S, Marshall
openaire   +2 more sources

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

PLoS Biology, 2018
The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain incompletely understood. Here, we report that soluble egg antigen (SEA) from Schistosoma mansoni, which
Maria M M Kaisar, Manuel Ritter, Carlos Del Fresno, Hulda S Jónasdóttir, Alwin J van der Ham, Leonard R Pelgrom, Gabriele Schramm, Laura E Layland, David Sancho, Clarissa Prazeres da Costa, Martin Giera, Maria Yazdanbakhsh, Bart Everts   +12 more
doaj   +1 more source

The protein segregase VCP/p97 promotes host antifungal defense via regulation of SYK activation.

PLoS Pathogens
C-type lectin receptors (CLRs) are essential to execute host defense against fungal infection. Nevertheless, a comprehensive understanding of the molecular underpinnings of CLR signaling remains a work in progress.
Zhugui Shao, Li Wang, Limin Cao, Tian Chen, Xin-Ming Jia, Wanwei Sun, Chengjiang Gao, Hui Xiao   +7 more
doaj   +1 more source

Dectin-1 Deficiency and Mucocutaneous Fungal Infections [PDF]

New England Journal of Medicine, 2010
László, Maródi, Melinda, Erdös
openaire   +2 more sources

Association between polymorphisms in the genes encoding toll-like receptors and dectin-1 and susceptibility to invasive aspergillosis: a systematic review

Revista da Sociedade Brasileira de Medicina Tropical
Invasive aspergillosis is a common fungal infection in immunocompromised individuals. Some studies have shown that toll-like receptor and dectin-1 genetic polymorphisms may alter signaling pathways, thus increasing an individual’s susceptibility to ...
Daiane de Oliveira Cunha, Jacqueline Andréia Bernardes Leão-Cordeiro, Hellen da Silva Cintra de Paula, Fábio Silvestre Ataides, Vera Aparecida Saddi, Cesar Augusto Sam Tiago Vilanova-Costa, Antonio Márcio Teodoro Cordeiro Silva   +6 more
doaj   +1 more source

Dectin-1 embraces Candida glabrata [PDF]

Virulence, 2017
openaire   +2 more sources

Is human dectin-1 Y238X gene polymorphism related to susceptibility to recurrent vulvovaginal candidiasis?

Current Medical Mycology, 2016
Background and Purpose: Vulvovaginal candidiasis is a frequent disease affecting approximately more than %75 of all childbearing women at least once in their lifetime by overgrowth of opportunistic Candida species.
Nina zahedi, Saeed Abedian Kenari, Sahar Mohseni, Narges Aslani, Saham Ansari, Hamid Badali   +5 more
doaj  

Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival. [PDF]

Sci Immunol
Torigoe S, Salie S, Keeton R, Aylan B, Appelmelk BJ, Williams DL, Lowman DW, Sugiki T, Matsumoto S, Kawano A, Mizuno S, Matsuo K, Søndergaard JN, Wing JB, A Höft M, Shoesmith R, Ndengane M, Coussens AK, Willment JA, Gutierrez MG, Hoving JC, Yamasaki S, Brown GD.   +22 more
europepmc   +1 more source

Dectin-1 multimerization and signaling depends on fungal β-glucan structure and exposure. [PDF]

Biophys J, 2023
Anaya EU, Amin AE, Wester MJ, Danielson ME, Michel KS, Neumann AK.   +5 more
europepmc   +1 more source