Deep brain stimulation (DBS) is increasing in popularity due to its successful treatment of movement disorders and its relatively low risk profile. However, its use for refractory, chronic pain syndromes actually precedes its use in movement disorders.
James Dierkes+2 more
+7 more sources
Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul+9 more
core +3 more sources
Effect of neurostimulation on cognition and mood in refractory epilepsy. [PDF]
Epilepsy is a common, debilitating neurological disorder characterized by recurrent seizures. Mood disorders and cognitive deficits are common comorbidities in epilepsy that, like seizures, profoundly influence quality of life and can be difficult to ...
Chan, Alvin Y+3 more
core +1 more source
Perspective on the economic evaluation of deep brain stimulation [PDF]
Parkinson’s disease (PD) is an example of a disease area experiencing increasing use of deep brain stimulation (DBS) to treat symptoms. PD is a major cause of morbidity and has a substantial economic impact on the patients, their caregivers, the health ...
McIntosh, E.S.
core +3 more sources
Dopamine Dysregulation Syndrome and Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease [PDF]
Dopamine dysregulation syndrome is a complication of the dopaminergic treatment in Parkinson's disease that may be very disabling due to the negative impact that compulsive medication use may have on patients' social, psychological, and physical ...
De la Casa-Fages, Beatriz+1 more
core +3 more sources
Wireless Magnetothermal Deep Brain Stimulation [PDF]
Wireless deep brain stimulation of well-defined neuronal populations could facilitate the study of intact brain circuits and the treatment of neurological disorders.
Anikeeva, Polina Olegovna+4 more
core +1 more source
Neurosurgery for psychopaths? The problems of empathy and neurodiversity [PDF]
I argue that deep brain stimulation (DBS) is a bad approach for incarcerated psychopaths for two reasons. First, given what we know about psychopathy, empathy, and DBS, it is unlikely to function as an effective treatment for the moral problems that ...
Ramirez, Erick
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Deep brain stimulation modulates synchrony within spatially and spectrally distinct resting state networks in Parkinson's disease [PDF]
Oswal et al. characterise the effect of deep brain stimulation (DBS) on STN-cortical synchronisation in Parkinson-s disease. They propose that cortical driving of the STN in beta frequencies is subdivided anatomically and spectrally, corresponding to the
Beudel, Martijn+7 more
core +3 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source