Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease [PDF]
, 2021 Damage to specific brain circuits can cause specific neuropsychiatric symptoms. Therapeutic stimulation to these same circuits may modulate these symptoms.
Brodtmann A. +26 more
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Neural plasticity in human brain connectivity: the effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease. [PDF]
PLoS ONE, 2014 Positive clinical outcomes are now well established for deep brain stimulation, but little is known about the effects of long-term deep brain stimulation on brain structural and functional connectivity.
Tim J van Hartevelt +6 more
doaj +1 more source
Discovering Themes in Deep Brain Stimulation Research Using Explainable Artificial Intelligence
Biomedicines, 2023 Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a
Ben Allen
doaj +1 more source
Science Advances, 2022 Supplying wireless power is a challenging technical problem of great importance for implantable biomedical devices. Here, we introduce a novel implantable piezoelectric ultrasound energy–harvesting device based on Sm-doped Pb(Mg1/3Nb2/3)O3-PbTiO3 (Sm-PMN-
Zhang Tao +14 more
semanticscholar +1 more source
Neurofeedback using implanted deep brain stimulation electrodes in patients with Parkinson’s disease [PDF]
, 2023 Parkinson’s disease represents a frequently occurring disease which still requires development of further therapies with neurofeedback constituting one possible element.
Rohr, Manabu
core +1 more source
Deep brain stimulation for Parkinson's disease
Journal of Internal Medicine, 2022 Parkinson's disease (PD) is a progressive neurodegenerative illness with both motor and nonmotor symptoms. Deep brain stimulation (DBS) is an established safe neurosurgical symptomatic therapy for eligible patients with advanced disease in whom medical ...
M. Hariz, P. Blomstedt
semanticscholar +1 more source
A 16-Channel Low-Power Neural Connectivity Extraction and Phase-Locked Deep Brain Stimulation SoC [PDF]
IEEE Solid-State Circuits Letters, vol. 6, pp. 21-24, Jan. 2023, 2022 Growing evidence suggests that phase-locked deep brain stimulation (DBS) can effectively regulate abnormal brain connectivity in neurological and psychiatric disorders. This letter therefore presents a low-power SoC with both neural connectivity extraction and phase-locked DBS capabilities.
arxiv +1 more source
Nature Communications, 2022 Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with mild Alzheimer’s Disease. Outcomes from randomized clinical trials have shown that cognitive function improved in some patients but deteriorated in others.
Ana Sofía Ríos +31 more
semanticscholar +1 more source
Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance We studied deep brain stimulation effects in two types of dystonia and conclude that different specific connections between the pallidum and thalamus are responsible for optimal treatment effects.
A. Horn +24 more
semanticscholar +1 more source
Complications After Deep Brain Stimulation: A 21-Year Experience in 426 Patients
Frontiers in Aging Neuroscience, 2022 BackgroundDeep brain stimulation is an established treatment for movement disorders such as Parkinson’s disease, essential tremor, and dystonia. However, various complications that occur after deep brain stimulation are a major concern for patients and ...
In-Ho Jung +6 more
doaj +1 more source