Results 121 to 130 of about 5,166,382 (407)
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Nature, 1892 GEOLOGISTS have had to wait long for this very important work, but now that it lies before them, we believe that the general verdict will be that it was worth while to wait even sixteen years for a monograph so excellent in design and so complete in execution. It must not be forgotten, too, that much of the information contained in this volume has been
openaire +2 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Antares completed: First selected results
, 2009 In May 2008, the Antares collaboration has completed the construction of the first deep sea neutrino telescope in the Northern hemisphere. Antares is a 3D array of 900 photomultipliers held in the sea by twelve mooring lines anchored at a depth of 2500 m
Presani, Eleonora
core +1 more source
Derivation of Del180 from sediment core log data\u27 Implications for millennial-scale climate change in the Labrador Sea [PDF]
, 2001 Sediment core logs from six sediment cores in the Labrador Sea show millennial-scale climate variability during the last glacial by recording all Heinrich events and several major Dansgaard-Oeschger cycles.
A. E. Aksu +45 more
core +2 more sources
Major impacts of climate change on deep-sea benthic ecosystems
, 2017 The deep sea encompasses the largest ecosystems on Earth. Although poorly known, deep seafloor ecosystems provide services that are vitally important to the entire ocean and biosphere.
A. Sweetman +21 more
semanticscholar +1 more source
Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes
Nature Ecology &Evolution, 2017 Hydrothermal vents and methane seeps are extreme deep-sea ecosystems that support dense populations of specialized macrobenthos such as mussels. But the lack of genome information hinders the understanding of the adaptation of these animals to such ...
Jin Sun +14 more
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
AIP AdvancesThe instantaneous detonation model (IDM) is widely used in simulating underwater explosions due to its efficiency and ability to ignore the detonation reaction process.
Yi Hao +5 more
doaj +1 more source