Results 181 to 190 of about 5,166,382 (407)
Italian Deep-Sea Exploration in the Mediterranean [PDF]
, 1881 HENRY HILLYER GIGI IOLI
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
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Polish Maritime ResearchSolar-powered autonomous underwater vehicles (SAUVs) can harness sustainable natural energy, meaning that they are capable of providing long-term mission support. This paper describes ongoing development work on the overall design of a SAUV.
Yu Chunliang +6 more
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
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XXV.—Natural history notes from H.M. Indian marine survey steamer ‘Investigator,’ Commander R.F. Hoskyn, R.N., Commanding.—Series II., No. 1. On the results of deep-sea dredging during the season 1890–91 (continued) [PDF]
, 1894 A. Alcock
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
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Progress in Fishery SciencesThe abundant and widely distributed resources of small pelagic fish in marine ecosystems constitute significant targets for commercial fisheries. The Japanese anchovy (Engraulis japonicus) is a prominent representative of small pelagic fish and is ...
Wenwen WANG +6 more
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Sailing the Deep Blue Sea of Decaying Burgers Turbulence
, 1999 We study Lagrangian trajectories and scalar transport statistics in decaying Burgers turbulence. We choose velocity fields, solutions of the inviscid Burgers equation, whose probability distributions are specified by Kida's statistics.
Bauer, Michel, Bernard, Denis
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
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