Results 61 to 70 of about 42,582 (271)

Genome-wide investigation of defensin genes in apple (Malus×domestica Borkh.) and in vivo analyses show that MdDEF25 confers resistance to Fusarium solani

open access: yesJournal of Integrative Agriculture
Apple replant disease is a complex soil syndrome that occurs when the same fields are repeatedly utilized for apple orchard cultivation. It can be caused by various pathogens, and Fusarium solani is the main pathogen.
Mengli Yang   +16 more
doaj   +1 more source

Alpha-defensin-dependent enhancement of enteric viral infection

open access: yesPLoS Pathogens, 2017
The small intestinal epithelium produces numerous antimicrobial peptides and proteins, including abundant enteric α-defensins. Although they most commonly function as potent antivirals in cell culture, enteric α-defensins have also been shown to enhance ...
Sarah S. Wilson   +6 more
semanticscholar   +1 more source

Olive Mill Waste-Water Extract Enriched in Hydroxytyrosol and Tyrosol Modulates Host–Pathogen Interaction in IPEC-J2 Cells

open access: yesAnimals
The dietary supplementation of olive oil by-products, including olive mill waste-water (OMWW) in animal diets, is a novel application that allows for their re-utilization and recycling and could potentially decrease the use of antibiotics, antimicrobial ...
Flavia Ferlisi   +9 more
doaj   +1 more source

Hitting the Sweet Spot: Glycans as Targets of Fungal Defense Effector Proteins

open access: yesMolecules, 2015
Organisms which rely solely on innate defense systems must combat a large number of antagonists with a comparatively low number of defense effector molecules.
Markus Künzler
doaj   +1 more source

A novel bi-domain plant defensin MtDef5 with potent broad-spectrum antifungal activity binds to multiple phospholipids and forms oligomers

open access: yesScientific Reports, 2017
Defensins are cysteine-rich cationic antimicrobial peptides contributing to the innate immunity in plants. A unique gene encoding a highly cationic bi-domain defensin MtDef5 has been identified in a model legume Medicago truncatula.
K. T. Islam   +5 more
semanticscholar   +1 more source

Human β-defensin 4 – defensin without the “twist”

open access: yesPostępy Biochemii, 2016
β-defensins are small, cysteine-rich, cationic peptides that contribute to various processes related to both arms of host defense, the innate and adaptive immunities. All β-defensins are potent antimicrobials with activity targeting a broad range of pathogens.
Adam, Prahl   +3 more
openaire   +3 more sources

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

open access: yesAnimal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu   +11 more
wiley   +1 more source

α-Defensin HD5 Inhibits Human Papillomavirus 16 Infection via Capsid Stabilization and Redirection to the Lysosome

open access: yesmBio, 2017
α-Defensins are an important class of abundant innate immune effectors that are potently antiviral against a number of nonenveloped viral pathogens; however, a common mechanism to explain their ability to block infection by these unrelated viruses is ...
Mayim E. Wiens, Jason G. Smith
semanticscholar   +1 more source

The Chemistry and Biology of Theta Defensins [PDF]

open access: yesAngewandte Chemie International Edition, 2014
AbstractCyclic peptides are found in a diverse range of organisms and are characterized by their stability and role in defense. Why is only one class of cyclic peptides found in mammals? Possibly we have not looked hard enough for them, or the technologies needed to identify them are not fully developed.
Conibear, Anne C., Craik, David J.
openaire   +5 more sources

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

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