Results 81 to 90 of about 37,059 (248)
Integrative Zoology, EarlyView.ABSTRACT The increasing frequency and intensity of heatwaves—extreme thermal events characterized by prolonged supra‐optimal temperatures—exert profound impacts on global ecosystem stability and species interactions. While the disruptive effects of thermal stress on host physiology and gut microbiota are well documented, the role of cuticular ...
Jiyu Wu +3 more
wiley +1 more source
Defensin gene expression in the cornea
, 1998 To determine whether defensin genes are expressed in human corneas and bovine corneal keratocytes. In situ hybridization and immunohistochemistry were used to localize defensin mRNA and protein in normal and diseased human corneas.
Stark, W J +5 more
core +1 more source
Allergy, EarlyView.Three molecular profiles identified among Art v 1/Amb a 4‐sensitized patients: Art v 1 monosensitization, Amb a 4 monosensitization, and dual sensitization to both allergens. Art v 1 monosensitization was predominantly associated with allergic rhinitis, reflecting a classical airborne allergy pattern.
Enrico Scala +20 more
wiley +1 more source
Genome-level identification, gene expression, and comparative analysis of porcine
BMC Genetics, 2012 Background Beta-defensins (β-defensins) are innate immune peptides with evolutionary conservation across a wide range of species and has been suggested to play important roles in innate immune reactions against pathogens. However, the complete β-defensin
Choi Min-Kyeung +9 more
doaj +1 more source
Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures
Allergy, EarlyView.This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally +6 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
, 2001 A rich residential microflora is harboured by the distal outer root sheath of the hair follicle and the hair canal – normally without causing skin diseases.
Quinn, A. +9 more
core +2 more sources
The expression of β-defensin 2 in B16-mBD2 cells.
, 2013 B16 cells were transfected with the plasmid, pcDNA3.1(+)-Igκ-β-defensin 2, or control pcDNA3.1(+), respectively, and treated with G418 for the generation of β-defensin 2 stably-expressing cell clones.
Han-fang Mei (333162) +7 more
core +1 more source
British Journal of Haematology, EarlyView.The graphical abstract provides a view on selected aspects of the pathogenesis, risk stratification and treatment of acute GVHD. Summary Acute graft‐versus‐host disease (aGVHD) remains a major complication following allogeneic haematopoietic stem cell transplantation (allo‐HSCT), representing a leading cause of non‐relapse mortality (NRM) and ...
Hazim Khatib, Robert Zeiser
wiley +1 more source
The fight of innate immunity and abnormal cannabinoids against Candida infection
British Journal of Pharmacology, EarlyView.Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori +2 more
wiley +1 more source