Results 81 to 90 of about 42,582 (271)

Defensins in periodontal health

Indian Journal of Dental Research, 2015
Defensins are abundant and widely distributed peptides in human and animal tissues that are involved in host defence. Defensins not only have the ability to strengthen the innate immune system but can also enhance the adaptive immune system by chemotaxis of monocytes, T-lymphocytes, dendritic cells and mast cells to the infection site.
Taran Bedi, Jaideep Mahendra, N Ambalavanan   +2 more
openaire   +3 more sources

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Characterization of an endogenous gene expressed in Aedes aegypti using an orally infectious recombinant sindbis virus

Journal of Insect Science, 2001
Sindbis virus expression vectors have been used successfully to express and silence genes of interest in vivo in several mosquito species, including Aedes aegypti, Ae. albopictus, Ae. triseriatus, Culex pipiens, Armigeres subalbatus and Anopheles gambiae.
L.L. Cheng, L.C. Bartholomay, K.E. Olson, C. Lowenberger, J. Vizioli, S. Higgs, B.J. Beaty, B.M. Christensen   +7 more
doaj  

Research Note: Intestinal avian defensin 2 and robustness of chicks

Poultry Science
: Poultry production is an important agricultural sector for human food worldwide. Chicks after hatch often face health problems leading to economic losses that are deleterious for breeders. Avian defensin 2 (AvBD2) is a prominent host defense peptide of
Sonia Métayer Coustard, Christelle Rossignol, Anne Collin, Fany Blanc, Nathalie Lallier, Catherine Schouler, Elisabeth Le Bihan Duval, Angelique Travel, Anne-Christine Lalmanach   +8 more
doaj   +1 more source

Genome-level identification, gene expression, and comparative analysis of porcine ß-defensin genes

BMC Genetics, 2012
Background Beta-defensins (β-defensins) are innate immune peptides with evolutionary conservation across a wide range of species and has been suggested to play important roles in innate immune reactions against pathogens. However, the complete β-defensin
Choi Min-Kyeung, Le Minh, Nguyen Dinh, Choi Hojun, Kim Won, Kim Jin-Hoi, Chun Jungwan, Hyeon Jiyeon, Seo Kunho, Park Chankyu   +9 more
doaj   +1 more source

Scorpion Potassium Channel-blocking Defensin Highlights a Functional Link with Neurotoxin*

Journal of Biological Chemistry, 2016
The structural similarity between defensins and scorpion neurotoxins suggests that they might have evolved from a common ancestor. However, there is no direct experimental evidence demonstrating a functional link between scorpion neurotoxins and ...
Lanxia Meng, Zili Xie, Qian Zhang, Yang Li, Fan Yang, Zongyun Chen, Wenxin Li, Zhijian Cao, Yingliang Wu   +8 more
semanticscholar   +1 more source

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

The Alpha-defensin Test for Periprosthetic Joint Infection Responds to a Wide Spectrum of Organisms

Clinical Orthopaedics and Related Research, 2015
BackgroundThe alpha-defensin test has been previously demonstrated to be highly accurate in the diagnosis of prosthetic joint infection (PJI), nearly matching the Musculoskeletal Infection Society definition for PJI.
C. Deirmengian, K. Kardos, Patrick Kilmartin, Simmi Gulati, Patrick Citrano, R. Booth   +5 more
semanticscholar   +1 more source

Synovial interleukin‐6 point‐of‐care testing, alone and combined with D‐dimer, supports rapid diagnosis of periprosthetic joint infection

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Data on the reliability of point‐of‐care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) D‐dimer (DD), interleukin 6 (IL‐6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL‐6 and PCT in ...
Sujeesh Sebastian, Hibah Abdulwahab Abusulaiman, Veronika Achatz, Matteo Spadini, Tobias Josef Niedrist, Markus Herrmann, Jochen Gerhard Hofstaetter   +6 more
wiley   +1 more source