Results 131 to 140 of about 28,067 (241)
Pantethine Restores Epidermal Homeostasis and Modulates Vesicle‐Associated Proteins in Psoriasis
Pantethine attenuates psoriasis‐like epidermal pathology in a full‐thickness 3D human skin model by modulating inflammatory, oxidative‐stress, differentiation and tissue‐remodelling responses, alongside changes in vesicle‐associated proteins. These findings support restoration of epidermal homeostasis, although direct effects on extracellular vesicles ...
Passanesh Sukphopetch +7 more
wiley +1 more source
Defensins In Ocular Immunity [PDF]
Corneal infection with P. aeruginosa results in corneal perforation in susceptible B6, but not resistant BALB/c mice. This study explored their role mBD 1-4 in corneal infection, and their potential synergy.
Wu, Minhao
core
Negative Role of the Receptor‐Like Kinase GbMIK2 in Regulating Cotton Verticillium Wilt Resistance
Upon infection with Verticillium dahliae, cotton plants induce the interaction between GbMIK2 and GbOCP3 at the cell membrane and in the nucleus, which blocks ROS burst and JA‐mediated resistance, resulting in suppression of cotton resistance to Verticillium wilt.
Chaowei Cai +17 more
wiley +1 more source
ABSTRACT Plant growth–promoting rhizobacteria (PGPR) have attracted increasing scientific interest due to their potential to enhance crop productivity and alleviate plant stress. An important trait of PGPR is the production of volatile organic compounds (VOCs), which can play crucial roles in plant–microbe and interspecies communication.
Aikaterini Triantafyllou +7 more
wiley +1 more source
Alcohol activates JNK2, leading to epithelial TJ disruption. Corticosterone activates JNK2 and causes Paneth cell dysfunction. Depletion of α‐defensins due to Paneth cell dysfunction causes gut microbiota dysbiosis. Microbiota dysbiosis and TJ disruption lead to endotoxemia, systemic inflammation, and liver damage.
Lohitha Basa +13 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Evgenii I. Olekhnovich +17 more
wiley +1 more source
From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley +1 more source
Defensins mediate skin inflammation and itch in psoriasis. [PDF]
Balaji SK +9 more
europepmc +1 more source
Defensins as natural antimicrobial peptide scaffolds against antimicrobial-resistant pathogens: mechanisms, resistance risks, and translational prospects. [PDF]
Abdallah EM +3 more
europepmc +1 more source

