Results 121 to 130 of about 28,067 (241)

Human alpha -defensins neutralize fibrinolytic activity exerted by staphylokinase

open access: yes, 2004
Defensins, cationic peptides with bacteriolytic properties, are abundantly found at inflammation sites and in human coronary vessels. Vascular occlusive diseases, such as myocardial infarction, pulmonary embolism, and peripheral arterial occlusion are ...
Bokarewa, Maria,, Tarkowski, Andrej,
core  

An Anatomist's View on the Crosstalk Between the Liver and the Lung

open access: yesComprehensive Physiology, Volume 16, Issue 6, December 2026.
The liver and the lung have a similar three‐dimensional and cellular architecture as well as functional communalities. The structural, functional, and pathophysiological interplay between both organs suggests the existence of an interorgan axis, the liver‐lung axis. Created in biorender.com.
Tanja Kloock   +2 more
wiley   +1 more source

[Scorpion toxins and defensins].

open access: yesComptes rendus des seances de la Societe de biologie et de ses filiales, 1998
Les venins de scorpion contiennent un grand nombre de neurotoxines peptidiques qui constituent un ensemble de familles molécu­laires à haut degré de polymorphisme, mais qui ont en commun une architecture semblable. Cette architecture se retrouve dans des peptides antibactériens circulants de la famille des défensines, qui s'apparentent tout ...
Goyffon, M, Landon, C.
openaire   +2 more sources

Synovial interleukin‐6 point‐of‐care testing, alone and combined with D‐dimer, supports rapid diagnosis of periprosthetic joint infection

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 10, Page 3627-3636, October 2026.
Abstract Purpose Data on the reliability of point‐of‐care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) D‐dimer (DD), interleukin 6 (IL‐6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL‐6 and PCT in ...
Sujeesh Sebastian   +6 more
wiley   +1 more source

Structural and Stability Analysis of de Novo Designed Proteins Incorporating a Plant Self‐Incompatibility Motif

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 12, Page 1990-2001, December 2026.
ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi   +7 more
wiley   +1 more source

Preliminary Evidence Suggests the Transcriptomic Response of Tricolored Bats to White‐Nose Syndrome Is Similar but Not Identical to That of Little Brown Bats

open access: yesEcology and Evolution, Volume 16, Issue 11, November 2026.
In this study, we evaluate gene expression of tricolored bats in response to white‐nose syndrome and compare it to that of little brown bats. We found that tricolored bats show evidence of a similar transcriptomic immune response to little brown bats, sharing pathways and some genes.
Robert E. Kwait   +5 more
wiley   +1 more source

Lost and Found: Western Honey Bee (Apis mellifera) Matrix Metalloproteinase 1

open access: yesEcology and Evolution, Volume 16, Issue 11, November 2026.
Despite considerable overall improvements in the Western honey bee (Apis mellifera) reference genome over the past two decades, some genes are missing in the current reference assembly (Amel_HAv3.1), potentially interfering with the meaningfulness of downstream analyses.
Jessica Braunisch   +4 more
wiley   +1 more source

Longitudinal Changes in Stone Composition and Histopathological and Proteomic Characterization of a Matrix Stone: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Matrix stones are rare urinary calculi composed predominantly of organic matrix, with poorly understood pathogenesis. We herein report a case involving refractory matrix stones with longitudinal compositional changes and characterize the final specimen using histopathological and proteomic analyses. Case Presentation A 54‐year‐old
Yuki Hideo   +4 more
wiley   +1 more source

Helicobacter pylori Infection Remodels Neutrophil‐Derived Extracellular Vesicles, Promoting Stress and Apoptosis in Infected Epithelial Cells

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
We report that Helicobacter pylori reprograms neutrophils to release extracellular vesicles (HPN‐EVs) with distinct biophysical and molecular features. These neutrophil‐derived vesicles, enriched in neutrophil granule proteins, LL‐37 and pro‐apoptotic miRNAs, suppress epithelial PI3K/Akt signalling, increase ROS, and induce mitochondrial dysfunction ...
Anand Kumar Keshri   +7 more
wiley   +1 more source

Molecular Recognition of Dental Resin Monomers by Salivary Proteins: Integrated Docking, DFT, Molecular Dynamics, and MM/PBSA Analysis

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
An integrated computational framework reveals distinct interaction patterns of dental resin monomers with key salivary proteins. Bis‐GMA shows the most favorable predicted binding profile, HEMA displays weaker and more variable interactions, and TEGDMA exhibits intermediate behavior.
Ravinder S. Saini   +10 more
wiley   +1 more source

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