Results 141 to 150 of about 42,072 (251)
Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 5, Page 1725-1739, May 2026.This meta‐analysis suggests that NGS of sonicate fluid demonstrates higher sensitivity compared to NGS of synovial fluid or periprosthetic tissue, while maintaining strong specificity, making it valuable for detecting infection. Periprosthetic tissue NGS demonstrated exceptional specificity and acceptable sensitivity, making it valuable for confirming ...
Lina Wang +6 more
wiley +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Alpha-defensin binding expands human adenovirus tropism.
PLoS PathogensMammalian α-defensins are a family of abundant effector peptides of the mucosal innate immune system. Although primarily considered to be antimicrobial, α-defensins can increase rather than block infection by certain prominent bacterial and viral ...
Cheng Zhao +4 more
doaj +1 more source
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.This study demonstrated that the pathogen responsible for diarrhoea in a cynomolgus monkey was identified as Proteus mirabilis (P. mirabilis) through methods including bacterial isolation and culture, morphological examination, biochemical profiling, 16S rRNA sequencing, analysis of key virulence genes and bacterial artificial infection tests.
Heling Li +6 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.YSK‐AB, a botanical mixture, reduced nitric oxide production in RAW 264.7 cells and chemokine expression in canine keratinocytes, suggesting its potential as a natural therapeutic agent for inflammatory skin diseases in dogs. ABSTRACT Background Botanical ingredients can function as adjunctive therapies for managing inflammatory skin diseases ...
Danbee Ha +3 more
wiley +1 more source
[Scorpion toxins and defensins].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1998 Les venins de scorpion contiennent un grand nombre de neurotoxines peptidiques qui constituent un ensemble de familles moléculaires à haut degré de polymorphisme, mais qui ont en commun une architecture semblable. Cette architecture se retrouve dans des peptides antibactériens circulants de la famille des défensines, qui s'apparentent tout ...
Goyffon, M, Landon, C.
openaire +2 more sources
Aging Cell, Volume 25, Issue 5, May 2026.A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins +8 more
wiley +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Anaerobe‐Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Background Genital microbiome dysbiosis is an important risk factor for the sexual acquisition of human immunodeficiency virus (HIV) in both the male and female genital tracts. The vaginal, penile and urethral mucosae are distinct microenvironments with characteristic microbiome compositions.
Shirley Constable +6 more
wiley +1 more source