Results 91 to 100 of about 9,786 (244)

Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan. [PDF]

, 2014
BACKGROUND: There is a need to standardise non-invasive measurements of liver iron concentrations (LIC) so clear inferences can be drawn about body iron levels that are associated with hepatic and extra-hepatic complications of iron overload.
Dudley J Pennell, E Angelucci, E Angelucci, E Butensky, Gillian Smith, GM Brittenham, GM Brittenham, HG Kreeftenberg, J Porter, J Porter, JB Porter, JB Porter, JC Wood, JC Wood, JC Wood, JM Bland, John B Porter, John-Paul Carpenter, JS Hankins, LJ Anderson, M Barry, M Puliyel, M Ropert-Bouchet, MA Tanner, MA Westwood, Maciej W Garbowski, MB McCarville, MD Cappellini, MD Cappellini, Michael Roughton, MJ Emond, MJ Soriano, Mohammed H Alam, NR Ghugre, P Kirk, PD Jensen, R Fischer, R Origa, RW Chapman, T He, Taigang He, TG St Pierre, TG St Pierre, Y Aydinok, Y Deugnier, Y Feng, Y Gandon   +46 more
core   +1 more source

Pengaruh Deferasirox Terhadap Kadar T4 dan TSH Pada B-Thalassemia Mayor dengan Kadar Ferritin Tinggi

Sari Pediatri, 2016
Latar belakang. Iron overload pada pasien 􀁂-thalassemia mayor terjadi akibat transfusi berulang. Pengendapan besi terjadi terutama di jantung, hati dan kelenjar endokrin.
Dewi Ratih P, Rudy Susanto, Bambang Sudarmanto   +2 more
doaj   +1 more source

Impact of iron chelation with deferasirox on telomere length and oxidative stress in hemodialysis patients: A randomized study

Nefrología
Background: Recent studies have demonstrated the effectiveness, safety, and tolerability of deferasirox in patients in peritoneal dialysis, however, its effect has not been studied in patients undergoing hemodialysis. Objective: To investigate the impact
Blanca Olivia Murillo Ortiz, Joel Ramírez Emiliano, Marcos Javier Romero Vázquez, Lauro Fabián Amador Medina, Sandra Martínez Garza, Edna Montserrat Ramos Rodríguez   +5 more
doaj   +2 more sources

Corrigendum

ClinicoEconomics and Outcomes Research, 2011
York Zoellner1, Maria-Magdalena Balp2, Andrea Gili Marco21Hamburg University of Applied Sciences, Hamburg, Germany; 2Novartis Pharma AG, Basel, SwitzerlandThe role of galenic innovation in improving treatment compliance and persistence: three case ...
Zoellner Y, Balp MM, Gili Marco A
doaj  

Drug-induced renal Fanconi syndrome [PDF]

, 2016
A number of therapeutic drugs are toxic to the kidney proximal tubule (PT) and can cause the renal Fanconi syndrome (FS). The most frequently implicated drugs are cisplatin, ifosfamide, tenofovir, sodium valproate and aminoglycoside antibiotics, and the ...
Bass, P., Hall, A.M., Unwin, R.J.
core  

A pharmaco-economic evaluation of deferasirox for treating patients with iron overload caused by transfusion-dependent thalassemia in Taiwan

Journal of the Formosan Medical Association, 2013
The newly available iron chelator deferasirox (Exjade, Novartis) is expected to provide better long-term clinical outcomes and improved quality of life for patients with thalassemia than its predecessor, deferoxamine (Desferal, Novartis), because of its ...
Wan-Ling Ho, Kuo-Piao Chung, Szu-Sheng Yang, Meng-Yao Lu, Shiann-Tarng Jou, Hsiu-Hao Chang, Yung-Li Yang, Dong-Tsamn Lin, Kai-Hsin Lin   +8 more
doaj   +1 more source

Methods and Challenges in Purifying Drug‐Loaded Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 14, Issue 6, June 2025.
ABSTRACT Extracellular vesicles (EV) have emerged as promising nanocarriers for drug delivery. However, the efficient loading of therapeutic molecules into EV and the subsequent purification of drug‐loaded EV from unloaded drugs remain significant challenges. This review explores the most used methods for EV purification, meaning the separation of drug‐
Marie Auquière, Giulio G. Muccioli, Anne des Rieux   +2 more
wiley   +1 more source

Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation. [PDF]

, 2011
Although fluoroquinolones or other antibiotics are commonly used to prevent bacterial infections after hematopoietic cell transplantation (HCT), because of the growing presence of multidrug-resistant microorganisms, it is important to identify patients ...
Ichinohe, T, Ichiyama, S, Ishikawa, T, Kanda, J, Kawabata, H, Kondo, T, Mizumoto, C, Saito, T, Takakura, S, Uchiyama, T, Yamashita, K   +10 more
core   +1 more source

Acute splenomegaly, haemolysis, and thrombocytopenia following luspatercept initiation in a patient with transfusion‐dependent thalassaemia: A case report

British Journal of Haematology, Volume 206, Issue 6, Page 1806-1810, June 2025.
Summary Patients with transfusion‐dependent thalassaemia (TDT) require chronic, life‐sustaining red blood cell transfusions, which contribute to iron overload and associated morbidity and mortality. Luspatercept, an inhibitor of the transforming growth factor‐beta pathway, decreases transfusion requirements in a subset of transfusion‐dependent β ...
Bianca Zaidel, Stephanie Garland, Hayley Merkeley   +2 more
wiley   +1 more source

Bilateral Nuclear Cataract with Deferasirox in a Patient of Beta-thalassemia: A Case Report and Literature Review

Delhi Journal of Ophthalmology
We report the case of a 15-year-old child with beta-thalassemia developing bilateral cataracts while receiving deferasirox, a newer iron chelator. She had been taking deferasirox for the past 10 years while receiving monthly blood transfusions.
Tushit Dhar, Vaishali Tomar, Subhash Dadeya   +2 more
doaj   +1 more source