MRI prospective survey on cardiac and hepatic iron in transfusion-dependent thalassemia intermedia patients treated with desferrioxamine, deferiprone and deferasirox [PDF]
, 2015 Alessia Pepe +9 more
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Deferasirox as adjunctive therapy for mucormycosis [PDF]
Journal of Antimicrobial Chemotherapy, 2011 Mucormycosis can be devastating and, as yet, there are no ideal therapies available. Observations that iron chelation may be a useful adjunct to antifungal treatment encouraged Spellberg et al. (J Antimicrob Chemother 2012; 715-22) to undertake a trial of deferasirox combined with liposomal amphotericin B (AmBisome(®)) as short-term therapy for ...
Donnelly, J.P., Lahav, M.
openaire +3 more sources
Beyond Simple Grinding: Methylammonium Chloride Promotes Sustainable, Cylinder-Free Mechanochemical Synthesis of Deferiprone. [PDF]
ChemSusChemDeferiprone is synthesized under solvent‐free mechanochemical conditions using ball milling. Methylammonium chloride and KOH enable efficient substitution of the oxygen atom in the maltol scaffold with a methylamine moiety, avoiding the limitations of methylamine solutions.
Basoccu F +6 more
europepmc +2 more sources
Nickel hydroxide films in contact with an electroactive solution. A study employing electrochemical impedance measurements [PDF]
, 2016 The deactivation of nickel hydroxide films after prolonged storage times without use was studied. This study was carried out in the context of the Rotating Disc Electrode Voltammetry (RDEV) andElectrochemical Impedance Spectroscopy (EIS) when the nickel ...
Tucceri, Ismael Ricardo
core +2 more sources
Cancer Medicine, 2019 Deferasirox is an oral iron‐chelating agent having possible antileukemia and immune modulatory effects. Few reports have evaluated deferasirox in the setting of allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We investigated the impact of
Byung‐Sik Cho +14 more
doaj +1 more source
Evaluation of Hepatic Enzymes in major β-thalassemic Patients using Deferasirox
Iraqi Journal of Pharmaceutical Sciences, 2022 β-thalassemia major is a genetic disease that causes sever defect in normal hemoglobin synthesis. The patients with β-thalassemia major need periodic blood transfusions that can result in accumulation of body iron, so treatment with iron chelating agent ...
Ahmed Yahya Dallal Bashi +1 more
doaj +1 more source
Invasive fungal infections secondary to traumatic injury [PDF]
, 2017 Invasive fungal infection (IFI) is a rare but serious complication of traumatic injury. The purpose of this article is to review the epidemiology, natural history, mycology, risk factors, diagnosis, treatment, and outcomes associated with post-traumatic ...
Bochicchio, Grant +5 more
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Hypersensitivity reaction with deferasirox
Journal of Pharmacology and Pharmacotherapeutics, 2015 Thalassemias comprise a group of hereditary blood disorders. Thalassemia major presents with anemia within the first 2 years of life requiring frequent blood transfusions for sustaining life. Regular blood transfusions lead to iron overload-related complications. Prognosis of thalassemia has improved because of the availability of iron-chelating agents.
Ekta Arora, Harmanjit Singh, Atul Sharma
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Deferasirox and renal dysfunction in children [PDF]
Pediatric Nephrology, 2012 Dear Sir, We read with great interest the recent article of Dubourg et al. published in Pediatric Nephrology [1]. In this timely article, the authors report their assessment of glomerular function, based on inulin clearance (20 % fall), estimated glomerular filtration rate (eGFR; 17 % fall), and serum creatinine (30 % rise), in a cohort of ten ...
Shahina Daar, Sunil Bhandari
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A Study of the Charge Transport Process at Nickel Hydroxide-Gold Modified Electrodes employing Rotating Disc Electrode Voltammetry and Ac Impedance Measurements [PDF]
, 2014 The aim of the present work was study how the charge-transport process of a nickel hydroxide film electrochemically synthesized on a gold substrate is modified when the electrode is stored without use for long time.
Tucceri, Ismael Ricardo
core +3 more sources