Results 71 to 80 of about 13,011 (272)
Acta Paediatrica, EarlyView.ABSTRACT Aim Limited Canadian data on paediatric acute pancreatitis exist. A meta‐analysis of 48 studies reported equal prevalence of acute pancreatitis among various aetiologies, with rates of severe acute pancreatitis at 13.7% in North America.
Catherine Korman +12 more
wiley +1 more source
Oxidative Medicine and Cellular Longevity, 2021 Varicocele is characterized by testicular dysfunction that originates from hyperthermia and hypoxia, leading to defects in testicular tissue and altered spermatozoa structure and function.
M. Rahmani +9 more
semanticscholar +1 more source
PERBEDAAN KADAR SGOT, SGPT DAN GAMMA GT PADA PASIEN TALASEMIA BETA MAYOR DENGAN KELASI BESI DEFERASIROX DAN DEFERIPRONE [PDF]
, 2016 Background: Iron accumulation in liver in patient with major thalassemia which has already having repeated transfution could cause liver disfuntion. Iron chelation is understood to be needed to reduce the dysfunction of the liver.
Abdussalam, Reza +2 more
core
Pharmacological and clinical evaluation of deferasirox formulations for treatment tailoring
Scientific Reports, 2021 Deferasirox (DFX) is the newest among three different chelators available to treat iron overload in iron-loading anaemias, firstly released as Dispersible Tablets (DT) and more recently replaced by Film-Coated Tablets (FCT).
A. Piolatto +6 more
semanticscholar +1 more source
Cancer Science, EarlyView.This study aimed to evaluate transferrin receptor (TfR) expression in human esophageal squamous cell cancer (ESCC) specimens and investigate the correlation between TfR overexpression and clinicopathological characteristics. Furthermore, we explored the potential of targeting iron metabolism pathways as a novel therapeutic strategy for ESCC.
Naoki Ikenaga +16 more
wiley +1 more source
Iron Chelation Therapy With Deferasirox in Sickle Cell Disease With End-Stage Renal Disease [PDF]
, 2022 Ashok Raj +4 more
openalex +1 more source
Insights Into Macrophage Ferroptosis: Implications for Atherosclerosis
Cell Proliferation, EarlyView.Macrophage ferroptosis drives atherosclerosis by enhancing oxidative stress and inflammation, accelerating plaque progression and instability. Targeting macrophage ferroptosis presents a promising therapeutic strategy for atherosclerosis treatment.
Xiehui Chen, Xiangbo Liu, Changchun Zeng
wiley +1 more source
Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management [PDF]
, 2018 Patients with non-transfusion-dependent thalassemia (NTDT) experience many clinical complications despite their independence from frequent transfusions.
Bou-Fakhredin, Rayan +5 more
core +4 more sources
Journal of Clinical Nursing, EarlyView.ABSTRACT Aim To explore challenges parents of children with cancer encounter while providing complex medical care at home. Methods Design: Cross‐sectional convergent mixed‐methods study. Instruments: Questionnaire and open interviews that mirrored and complemented each other.
Rachel Klausner Shyman +5 more
wiley +1 more source
Long-term persistency and costs associated with the use of iron chelation therapies in the treatment of Sickle cell disease within Medicaid programs. [PDF]
, 2013 OBJECTIVE: This retrospective study evaluated iron chelating therapy (ICT) discontinuation and costs in Sickle cell disease (SCD) Medicaid recipients using healthcare claims from 2006-2010.
Armstrong, Edward P +4 more
core +1 more source