Results 101 to 110 of about 5,736 (192)

Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis

, 2006
Most deaths in beta-thalassemia major result from cardiac complications due to iron overload. Differential effects on myocardial siderosis may exist between different chelators.
Gotsis, ED, Karagiorga, M, Berdoukas, V, Aessopos, A, Tanner, MA, Galanello, R, Pennell, DJ, Piga, A, Smith, GC, Westwood, MA, Ladis, V, Wonke, B   +11 more
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Cataract Formation due to use of Deferiprone in a Patient with Thalassemia Major

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Thalassemias are a heterogeneous group of autosomal recessive diseases characterized by hypochromic microcytic anemia and occur as a result of defective synthesis of one or more hemoglobin chains. In patients, life-threatening clinical manifestations may
Barbaros sahin Karagun, Yurdanur Kilinc, ilgen sasmaz, Ali Bulent Antmen   +3 more
doaj  

Therapeutic modalities of deferiprone in Parkinson's disease: SKY and EMBARK studies

International audienceBackground Reducing nigrostriatal iron overload reduces neuronal loss in Parkinson's disease (PD) models. Objective Examine the safety and efficacy of deferiprone in reducing motor disability progression in dopaminergic-treated and ...
Toiber Temin, Noemi, Drapier, S., Devos, D., Pavese, N., Corvol, J. C., Suchowersky, Oksana, Temin, N. T., Kalia, L. V., Pape, Heidi, Foubert-Samier, A., Lewis, S., Tricta, F., Devos, David, Kalia, Lorraine, V, Fradette, C., Pavese, Nicola, Tricta, Fernando, TRANCHANT, Christine, Sheridan, R., Berg, D., Fradette, Caroline, Tranchant, C., KALIA, Lorraine V, Berg, Daniela, Remy, P., TEMIN, Noemi Toiber, Couratier, P., Danaila, T., Corvol, Jean-Christophe, Danaila, Teodor, Moreau, Caroline, Geny, C., Rascol, O., Evans, Andrew, Burn, D., Anheim, M., SAMIER FOUBERT, Alexandra, Geny, Christian, Moreau, C., Drapier, Sophie, Raw, J., Carroll, Camille, Burn, David, Schnitzler, A., Raw, Jason, Meissner, W. G., Eggert, K., Eggert, Karla, Maltête, David, Evans, A., Carroll, C., Couratier, Philippe, Rémy, Philippe, Sheridan, Ray, Defer, Gilles, Anheim, Mathieu, Foubert-Samier, Alexandra, RASCOL, Olivier, Tranchant, Christine H., Schnitzler, Alfons, Maltête, D., Suchowersky, O., Rascol, Olivier J., A PARKINSON'S DISEASE STUDY, Group, Defer, G., Meissner, Wassilios, Pape, H., Lewis, Simon, MEISSNER, Wassilios G   +68 more
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Dual oral iron chelation with deferasirox and deferiprone in transfusion-dependent β-thalassemia: a narrative review of efficacy, safety, and practical application. [PDF]

Ann Hematol
James V, Emeghebo KI.
europepmc   +1 more source

Triple Iron Chelation in Transfusion Dependent Thalassemia: A Case Report. [PDF]

J Clin Med
Njue L, Häfliger E, Rovó A.
europepmc   +1 more source

The in vitro activity of iron chelator deferiprone against Candida (Candidozyma) auris in combination with antifungal agents. [PDF]

Med Mycol
Tóth Z, Farkas B, Majoros L, Jakab Á, Borman AM, Varga I, Tóth PR, Kovács R.   +7 more
europepmc   +1 more source

Machine learning-assisted screening of small-molecule drugs for suppressing protein aggregation and ROS generation based on ECL and CV dual-mode signals amplified by DNA. [PDF]

Chem Sci
Shi J, Zhu W, Yan J, Xiao C, Yao H, Meng L, Liu H, Mao L.   +7 more
europepmc   +1 more source

Management of iron overload in adult myelodysplastic syndrome. [PDF]

Hematology Am Soc Hematol Educ Program
Leitch HA, Buckstein R.
europepmc   +1 more source

Efficacy of combination chelation with deferasirox and deferiprone in children with beta-thalassemia major: an audit from a unit in the developing world. [PDF]

Clin Exp Med
James V, Prakash A.
europepmc   +1 more source

Deferiprone as an oral iron chelator in sickle cell disease

, 2007
Iron overload is not uncommon in sickle cell disease (SCD) and requires regular chelation therapy in several instances. The present study evaluates the effect of deferiprone in 15 adult patients with SCD (ten beta(s)/beta(0)thalassemia and five beta(s ...
Meletis, J, Ourailidis, A, Voskaridou, E, Papassotiriou, I, Douskou, M, Terpos, E, Stamoulakatou, A, Loukopoulos, D   +7 more
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