PLoS ONE, 2021 IntroductionAdhesions are often considered to be an inevitable consequence of abdominal and pelvic surgery, jeopardizing the medium and long-term success of these procedures.
Rajan Sundaresan Vediappan +12 more
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A label-free fluorescent probe for deferiprone quantification in exhaled breath condensate utilizing UiO-66 MOF/ferric ions system [PDF]
Scientific ReportsThis study developed a simple and label-free fluorescent probe for deferiprone quantification in exhaled breath condensate (EBC) samples. For that, UiO-66, synthesized in a one-step process with the solvothermal method, along with ferric ions, provided a
Nima Sheikh Abdollahzadeh Mamaghani +5 more
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Solubility and thermodynamic study of deferiprone in propylene glycol and ethanol mixture [PDF]
BMC Chemistry, 2023 This work aims to obtain the solubility, density and thermodynamic parameters of deferiprone in propylene glycol and ethanol. For this purpose, a shake-flask technique was applied for solid–liquid equilibration and the spectrophotometry method was ...
Samira Radmand +4 more
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A pilot trial of deferiprone for neurodegeneration with brain iron accumulation
Haematologica, 2011 Deferiprone was shown to reverse iron deposition in Friedreich’s ataxia. This multi-center, unblinded, single-arm pilot study evaluated safety and efficacy of deferiprone for reducing cerebral iron accumulation in neurodegeneration with brain iron ...
Giovanni Abbruzzese +11 more
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Amphetamine-like Deferiprone and Clioquinol Derivatives as Iron Chelating Agents [PDF]
MoleculesThe accumulation of iron in dopaminergic neurons can cause oxidative stress and dopaminergic neuron degeneration. Iron chelation therapy may reduce dopaminergic neurodegeneration, but chelators should be targeted towards dopaminergic cells. In this work,
Mahmoud El Safadi +6 more
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Chelation Therapy with Oral Solution of Deferiprone in Transfusional Iron-Overloaded Children with Hemoglobinopathies [PDF]
Anemia, 2013 Iron overload in hemoglobinopathies is secondary to blood transfusions, chronic hemolysis, and increased iron absorption and leads to tissue injury requiring the early use of chelating agents.
Alexandros Makis +4 more
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Design and development of metal-organic framework-based nanocomposite hydrogels for quantification of deferiprone in exhaled breath condensate [PDF]
BMC ChemistryIn this study, a novel fluorescence nanoprobe based on Materials of Institute Lavoisier (MIL-101) metal-organic frameworks embedding into the agarose hydrogel is fabricated using a hydrothermal technique.
Reza Moharami +6 more
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Brain Sciences, 2018 The CAALA (Complex Augmentation of ALA) regimen was developed with the goal of redressing some of the weaknesses of 5-aminolevulinic acid (5-ALA) use in glioblastoma treatment as it now stands.
Richard E. Kast +8 more
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Comparative Efficacy of Deferiprone, Deferoxamine and Combination of Deferiprone and Deferoxamine on Serum Ferritin Value in Beta-Thalassemia Patients [PDF]
Journal of Krishna Institute of Medical Sciences University, 2015 Background: Iron overload is a predictable and lifethreatening complication in patients with thalassemia. Effective and convenient iron chelation remains one of the main targets of clinical management of thalassemia major.
Nargesbeygom Mirbehbahani +3 more
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The in vitro activity of iron chelator deferiprone against Candida (Candidozyma) auris in combination with antifungal agents. [PDF]
Med MycolTóth Z +7 more
europepmc +3 more sources