Results 11 to 20 of about 1,030,335 (270)
Morphometric analyses of the visual pathways in macular degeneration [PDF]
Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated.
Baseler, Heidi A. +8 more
core +5 more sources
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration [PDF]
Axonal degeneration is a molecular self-destruction cascade initiated following traumatic, toxic, and metabolic insults. Its mechanism underlies a number of disorders including hereditary and diabetic neuropathies and the neurotoxic side effects of ...
Bhattacharya, Martha R.C. +7 more
core +2 more sources
Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]
BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A +5 more
core +3 more sources
Semi-Stable Degeneration of Toric Varieties and Their Hypersurfaces [PDF]
We provide a construction of examples of semistable degeneration via toric geometry. The applications include a higher dimensional generalization of classical degeneration of K3 surface into 4 rational components, an algebraic geometric version of ...
Hu, Shengda
core +2 more sources
Mitochondria are the main sites of biological energy generation in eukaryotes. These organelles are remnants of a bacterial endosymbiont that took up residence inside a host cell over 1,500 million years ago. Comparative genomics studies suggest that the mitochondrion is monophyletic in origin.
Mark, van der Giezen, Jorge, Tovar
openaire +2 more sources
Complement C3 variant and the risk of age-related macular degeneration [PDF]
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM +16 more
core +1 more source
On the Euler characteristic of Kronecker moduli spaces [PDF]
Combining the MPS degeneration formula for the Poincar\'e polynomial of moduli spaces of stable quiver representations and localization theory, it turns that the determination of the Euler characteristic of these moduli spaces reduces to a combinatorial ...
Weist, Thorsten
core +1 more source
Injectable bone biomaterials like bone cement should be designed and fabricated with certain biological criteria, which include: 1) recruitment and polarization of the macrophages from M1 (pro-inflammatory) to M2 (anti-inflammatory) phenotype, 2) enhance
Shuaijie Li +12 more
doaj +1 more source
$E_1$-degeneration and $d'd''$-lemma [PDF]
For a double complex $(A, d', d'')$, we show that if it satisfies the $d'd''$-lemma and the spectral sequence $\{E^{p, q}_r\}$ induced by $A$ does not degenerate at $E_0$, then it degenerates at $E_1$.
Chen, Tai-Wei +2 more
core +2 more sources
Recently, various studies have identified circular RNAs (circRNAs) to play a significant role in tumorigenesis, thereby showing potential as novel tumor biomarkers.
Yining Xu +12 more
doaj +1 more source

