Results 11 to 20 of about 1,030,335 (270)

Morphometric analyses of the visual pathways in macular degeneration [PDF]

open access: yes, 2014
Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated.
Baseler, Heidi A.   +8 more
core   +5 more sources

A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration [PDF]

open access: yes, 2012
Axonal degeneration is a molecular self-destruction cascade initiated following traumatic, toxic, and metabolic insults. Its mechanism underlies a number of disorders including hereditary and diabetic neuropathies and the neurotoxic side effects of ...
Bhattacharya, Martha R.C.   +7 more
core   +2 more sources

Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]

open access: yes, 2013
BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A   +5 more
core   +3 more sources

Semi-Stable Degeneration of Toric Varieties and Their Hypersurfaces [PDF]

open access: yes, 2006
We provide a construction of examples of semistable degeneration via toric geometry. The applications include a higher dimensional generalization of classical degeneration of K3 surface into 4 rational components, an algebraic geometric version of ...
Hu, Shengda
core   +2 more sources

Degenerate mitochondria [PDF]

open access: yesEMBO reports, 2005
Mitochondria are the main sites of biological energy generation in eukaryotes. These organelles are remnants of a bacterial endosymbiont that took up residence inside a host cell over 1,500 million years ago. Comparative genomics studies suggest that the mitochondrion is monophyletic in origin.
Mark, van der Giezen, Jorge, Tovar
openaire   +2 more sources

Complement C3 variant and the risk of age-related macular degeneration [PDF]

open access: yes, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM   +16 more
core   +1 more source

On the Euler characteristic of Kronecker moduli spaces [PDF]

open access: yes, 2012
Combining the MPS degeneration formula for the Poincar\'e polynomial of moduli spaces of stable quiver representations and localization theory, it turns that the determination of the Euler characteristic of these moduli spaces reduces to a combinatorial ...
Weist, Thorsten
core   +1 more source

Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects

open access: yesBioactive Materials, 2023
Injectable bone biomaterials like bone cement should be designed and fabricated with certain biological criteria, which include: 1) recruitment and polarization of the macrophages from M1 (pro-inflammatory) to M2 (anti-inflammatory) phenotype, 2) enhance
Shuaijie Li   +12 more
doaj   +1 more source

$E_1$-degeneration and $d'd''$-lemma [PDF]

open access: yes, 2015
For a double complex $(A, d', d'')$, we show that if it satisfies the $d'd''$-lemma and the spectral sequence $\{E^{p, q}_r\}$ induced by $A$ does not degenerate at $E_0$, then it degenerates at $E_1$.
Chen, Tai-Wei   +2 more
core   +2 more sources

Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway

open access: yesFrontiers in Cell and Developmental Biology, 2021
Recently, various studies have identified circular RNAs (circRNAs) to play a significant role in tumorigenesis, thereby showing potential as novel tumor biomarkers.
Yining Xu   +12 more
doaj   +1 more source

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