Results 11 to 20 of about 894,956 (297)

Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

Journal of Immunology Research, 2023
Diffuse alveolar haemorrhage (DAH) is a rapidly developing condition owing to a lack of effective treatment and resulting in a high mortality rate in systemic lupus erythematosus (SLE).
Xinai Han, Xiaoming Zhang, Rui Song, Shiqi Li, Shujing Zou, Quanguang Tan, Tianyang Liu, Shugeng Luo, Zhe Wu, Hongyu Jie, Jinhong Wang   +10 more
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Augmenting MNK1/2 activation by c-FMS proteolysis promotes osteoclastogenesis and arthritic bone erosion

Bone Research, 2021
Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA).
Se Hwan Mun, Seyeon Bae, Steven Zeng, Brian Oh, Carmen Chai, Matthew Jundong Kim, Haemin Kim, George Kalliolias, Chitra Lekha Dahia, Younseo Oh, Tae-Hwan Kim, Jong Dae Ji, Kyung-Hyun Park-Min   +12 more
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MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS

Bone Research, 2021
Osteoporosis is a metabolic bone disease with dysregulated coupling between bone resorption and bone formation, which results in decreased bone mineral density.
Takayuki Fujii, Koichi Murata, Se-Hwan Mun, Seyeon Bae, Ye Ji Lee, Tannia Pannellini, Kyuho Kang, David Oliver, Kyung-Hyun Park-Min, Lionel B. Ivashkiv   +9 more
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Comparison of category and letter fluency tasks through automated analysis

Frontiers in Psychology, 2023
IntroductionCategory and letter fluency tasks are commonly used neuropsychological tasks to evaluate lexical retrieval.MethodsThis study used validated automated methods, which allow for more expansive investigation, to analyze speech production of both ...
Carmen Gonzalez-Recober, Naomi Nevler, Sanjana Shellikeri, Katheryn A. Q. Cousins, Emma Rhodes, Mark Liberman, Murray Grossman, David Irwin, Sunghye Cho   +8 more
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Social and leisure activity are associated with attenuated cortical loss in behavioral variant frontotemporal degeneration

NeuroImage: Clinical, 2021
Behavioral variant frontotemporal degeneration (bvFTD) is clinically characterized by progressive decline in social and executive domains. Previous work suggests that early lifestyle factors such as education and occupational attainment may relate to ...
Nikolas G. Kinney, Jessica Bove, Jeffrey S. Phillips, Katheryn A.Q Cousins, Christopher A. Olm, Daniel G. Wakeman, Corey T. McMillan, Lauren Massimo   +7 more
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Automated Analysis of Digitized Letter Fluency Data

Frontiers in Psychology, 2021
The letter-guided naming fluency task is a measure of an individual’s executive function and working memory. This study employed a novel, automated, quantifiable, and reproducible method to investigate how language characteristics of words produced ...
Sunghye Cho, Naomi Nevler, Natalia Parjane, Christopher Cieri, Mark Liberman, Murray Grossman, Katheryn A. Q. Cousins   +6 more
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Caffeine Inhibits Oxidative Stress- and Low Dose Endotoxemia-Induced Senescence—Role of Thioredoxin-1

Antioxidants, 2023
The maintenance of Thioredoxin-1 (Trx-1) levels, and thus of cellular redox homeostasis, is vital for endothelial cells (ECs) to prevent senescence induction.
Dennis Merk, Jan Greulich, Annika Vierkant, Fiona Cox, Olaf Eckermann, Florian von Ameln, Nadine Dyballa-Rukes, Joachim Altschmied, Niloofar Ale-Agha, Philipp Jakobs, Judith Haendeler   +10 more
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Processing ambiguity in a linguistic context:Decision-making difficulties in non-aphasic patients with behavioral variant Frontotemporal Degeneration

Frontiers in Human Neuroscience, 2015
Some extent of ambiguity is ubiquitous in every day conversations. For example, words have multiple meaning and very common pronouns, like he and she (anaphoric pronouns), have little meaning on their own and refer to a noun that has been previously ...
Nicola eSpotorno, Meghan eHealey, Corey T. McMillan, Katya eRascovsky, David J Irwin, Robin eClark, Murray eGrossman   +6 more
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Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects

Bioactive Materials, 2023
Injectable bone biomaterials like bone cement should be designed and fabricated with certain biological criteria, which include: 1) recruitment and polarization of the macrophages from M1 (pro-inflammatory) to M2 (anti-inflammatory) phenotype, 2) enhance
Shuaijie Li, Liyan Zhang, Chunyu Liu, Jua Kim, Kun Su, Tingli Chen, Limin Zhao, Xiaomei Lu, Hao Zhang, Yinglin Cui, Xu Cui, Feng Yuan, Haobo Pan   +12 more
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Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway

Frontiers in Cell and Developmental Biology, 2021
Recently, various studies have identified circular RNAs (circRNAs) to play a significant role in tumorigenesis, thereby showing potential as novel tumor biomarkers.
Yining Xu, Yining Xu, Teng Yao, Haonan Ni, Rujie Zheng, Kangmao Huang, Yizhen Huang, Jun Gao, Di Qiao, Di Qiao, Shuying Shen, Jianjun Ma, Jianjun Ma   +12 more
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